MedPath

Anetumab ravtansine

Generic Name
Anetumab ravtansine
Brand Names
-
Drug Type
Biotech
Chemical Formula
-
CAS Number
1375258-01-7
Unique Ingredient Identifier
M170940PMI
Background

Anetumab ravtansine is under investigation in clinical trial NCT03455556 (Anetumab Ravtansine and Atezolizumab in Treating Participants With Advanced Non-small Cell Lung Cancer).

Associated Conditions
-
Associated Therapies
-

Testing the Combination of Anetumab Ravtansine With Either Nivolumab, Nivolumab and Ipilimumab, or Gemcitabine and Nivolumab in Advanced Pancreatic Cancer

Phase 1
Active, not recruiting
Conditions
Stage II Pancreatic Cancer AJCC v8
Stage III Pancreatic Cancer AJCC v8
Pancreatic Adenocarcinoma
Stage IV Pancreatic Cancer AJCC v8
Interventions
First Posted Date
2019-01-25
Last Posted Date
2024-12-27
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
74
Registration Number
NCT03816358
Locations
๐Ÿ‡บ๐Ÿ‡ธ

The University of Kansas Cancer Center - Olathe, Olathe, Kansas, United States

๐Ÿ‡บ๐Ÿ‡ธ

University of Alabama at Birmingham Cancer Center, Birmingham, Alabama, United States

๐Ÿ‡บ๐Ÿ‡ธ

City of Hope Comprehensive Cancer Center, Duarte, California, United States

and more 42 locations

Bevacizumab and Anetumab Ravtansine or Paclitaxel in Treating Patients With Refractory Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Phase 2
Active, not recruiting
Conditions
Fallopian Tube Endometrioid Adenocarcinoma
Fallopian Tube High Grade Serous Adenocarcinoma
Ovarian Endometrioid Adenocarcinoma
Platinum-Resistant Fallopian Tube Carcinoma
Platinum-Resistant Primary Peritoneal Carcinoma
Primary Peritoneal High Grade Serous Adenocarcinoma
Platinum-Resistant Ovarian Carcinoma
Ovarian High Grade Serous Adenocarcinoma
Interventions
First Posted Date
2018-07-16
Last Posted Date
2024-12-27
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
96
Registration Number
NCT03587311
Locations
๐Ÿ‡บ๐Ÿ‡ธ

The University of Kansas Cancer Center - Olathe, Olathe, Kansas, United States

๐Ÿ‡บ๐Ÿ‡ธ

UC Irvine Health/Chao Family Comprehensive Cancer Center, Orange, California, United States

๐Ÿ‡บ๐Ÿ‡ธ

UCHealth University of Colorado Hospital, Aurora, Colorado, United States

and more 20 locations

Pembrolizumab With or Without Anetumab Ravtansine in Treating Patients With Mesothelin-Positive Pleural Mesothelioma

Phase 1
Active, not recruiting
Conditions
Pleural Malignant Mesothelioma
Interventions
Biological: Anetumab Ravtansine
Other: Laboratory Biomarker Analysis
Biological: Pembrolizumab
Other: Pharmacological Study
First Posted Date
2017-04-24
Last Posted Date
2024-10-16
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
49
Registration Number
NCT03126630
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Mayo Clinic in Arizona, Scottsdale, Arizona, United States

๐Ÿ‡บ๐Ÿ‡ธ

Mayo Clinic Hospital in Arizona, Phoenix, Arizona, United States

๐Ÿ‡บ๐Ÿ‡ธ

UC San Diego Moores Cancer Center, La Jolla, California, United States

and more 30 locations

Anti-Mesothelin Antibody Drug Conjugate Anetumab Ravtansine for Mesothelin Expressing Lung Adenocarcinoma

Phase 2
Terminated
Conditions
Lung Neoplasms
Interventions
Drug: Anetumab Ravtansine
Device: Blood test
First Posted Date
2016-07-21
Last Posted Date
2019-05-21
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
2
Registration Number
NCT02839681
Locations
๐Ÿ‡บ๐Ÿ‡ธ

National Institutes of Health Clinical Center, Bethesda, Maryland, United States

ยฉ Copyright 2025. All Rights Reserved by MedPath