Spinosad
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Spinosad is a pediculicide used topically to treat head lice.
Spinosad is a pediculicide used topically to treat head lice.
Spinosad is a mixture of spinosyn A and spinosyn D in a 5:1 ratio. This combination causes neuronal hyperexcitation through mostly alteration of nicotinic acetylcholine receptors, which ultimately leads to lice paralysis and death.
Spinosad is indicated for the topical treatment of head lice infestation in adult and pediatric patients ≥6 months old. It is also indicated for the topical treatment of scabies infestation in adult and pediatric patients ≥4 years old.
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