Clopidogrel
- Generic Name
- Clopidogrel
- Brand Names
- Duoplavin, Plavix, Zyllt, Clopidogrel BGR (previously Zylagren), Clopidogrel TAD, Clopidogrel ratiopharm, Clopidogrel Zentiva (previously Clopidogrel Winthrop), Clopidogrel Krka, Clopidogrel Krka d.d. (previously Zopya), Clopidogrel Teva (hydrogen sulphate), Clopidogrel HCS, Iscover, Grepid, Clopidogrel Taw Pharma (previously Clopidogrel Mylan), Clopidogrel Viatris (previously Clopidogrel Taw Pharma)
- Drug Type
- Small Molecule
- Chemical Formula
- C16H16ClNO2S
- CAS Number
- 113665-84-2
- Unique Ingredient Identifier
- A74586SNO7
- Background
Clopidogrel is a prodrug of a platelet inhibitor used to reduce the risk of myocardial infarction and stroke. Clopidogrel is indicated to reduce the risk of myocardial infarction for patients with non-ST elevated acute coronary syndrome (ACS), patients with ST-elevated myocardial infarction, and in recent MI, stroke, or established peripheral arterial diseas...
- Indication
1.用于新近心肌梗死、新近脑卒中或确诊的周围动脉病变患者，可减少新的缺血性脑卒中、心肌梗死和死亡等心脑血管事件的符合终点；
2.用于急性冠状动脉综合征（不稳定心绞痛和非ST段抬高心肌梗死）患者；
3.用于冠状动脉支架置入术后预防支架内血栓形成（与阿司匹林联用）。
- Associated Conditions
- Acute Coronary Syndrome (ACS), Acute Myocardial Infarction (AMI), Cardiovascular Events, Atherothrombotic events
- Associated Therapies
- -
Evaluation of Platelet Aggregability in Patients With Previous Acute Myocardial Infarction or Concomitant Lower Extremity Peripheral Artery Disease
- Conditions
- Interventions
- First Posted Date
- 2024-06-12
- Last Posted Date
- 2024-06-12
- Lead Sponsor
- University of Sao Paulo
- Target Recruit Count
- 100
- Registration Number
- NCT06454045
- Locations
- 🇧🇷
Heart Institute (InCor) / University of São Paulo, São Paulo, Sao Paulo, Brazil
The Nordic Aortic Valve Intervention Trial 4 (NOTION-4)
- First Posted Date
- 2024-06-10
- Last Posted Date
- 2024-06-10
- Lead Sponsor
- Rigshospitalet, Denmark
- Target Recruit Count
- 324
- Registration Number
- NCT06449469
- Locations
- 🇩🇰
Aarhus University Hospital, Skejby, Aarhus, Denmark
🇩🇰Rigshospitalet, Copenhagen, Denmark
Clopidogrel Versus Cilostazol on Vessels
- Conditions
- Interventions
- First Posted Date
- 2024-05-07
- Last Posted Date
- 2024-05-07
- Lead Sponsor
- Seoul National University Bundang Hospital
- Target Recruit Count
- 120
- Registration Number
- NCT06402747
- Locations
- 🇰🇷
Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, Korea, Republic of
TADCLOT- a Double Blind Randomized Controlled Trial
- Conditions
- Interventions
- First Posted Date
- 2024-03-19
- Last Posted Date
- 2024-03-19
- Target Recruit Count
- 2200
- Registration Number
- NCT06318481
- Locations
- 🇵🇰
National Institute of Cardiovascular Diseases, Karachi, SIndh, Pakistan
Effects of Low-dose Ticagrelor vs. Clopidogrel in Stable Patients Undergoing Elective Percutaneous Coronary Intervention
- Conditions
- Interventions
- First Posted Date
- 2024-01-29
- Last Posted Date
- 2024-04-23
- Lead Sponsor
- University of Florida
- Target Recruit Count
- 50
- Registration Number
- NCT06228456
- Locations
- 🇺🇸
University of Florida Jacksonville, Jacksonville, Florida, United States
Effects of Antiplatelet and Antioxidant Agents on Drusen Progression: A Pilot, Prospective Cohort Study
- Conditions
- Interventions
- First Posted Date
- 2023-12-11
- Last Posted Date
- 2023-12-15
- Lead Sponsor
- Navamindradhiraj University
- Target Recruit Count
- 174
- Registration Number
- NCT06165068
- Locations
- 🇹🇭
Department of ophthalmology, Faculty of medicine, Vajira hospital, Navamindradhiraj University, Bangkok, Dusit, Thailand
Ticagrelor Versus Clopidogrel in Large Vessel Ischemic Stroke
- First Posted Date
- 2023-11-07
- Last Posted Date
- 2023-12-29
- Lead Sponsor
- Kafrelsheikh University
- Target Recruit Count
- 580
- Registration Number
- NCT06120725
- Locations
- 🇪🇬
Kafr Elsheikh University Hospital, Kafr Ash Shaykh, Egypt
Efficacy of Colchicine in Preventing Recurrent Stroke in the Patients With Acute Atherothrombotic Ischemic Stroke During Hospitalization
- First Posted Date
- 2023-10-26
- Last Posted Date
- 2023-11-07
- Lead Sponsor
- Mikhail Zykov
- Target Recruit Count
- 200
- Registration Number
- NCT06102720
- Locations
- 🇷🇺
Sochi City Hospital #4, Sochi, Krasnodar Refion, Russian Federation
🇷🇺Research Institute for Complex Issues of Cardiovascular Diseas, Kemerovo, Kemerovo Region, Russian Federation
Ticagrelor Single Antiplatelet Therapy in Patients With High Risk of Bleeding After DCB for Coronary Small Vessel Disease
- Conditions
- Interventions
- First Posted Date
- 2023-10-18
- Last Posted Date
- 2023-10-18
- Lead Sponsor
- Fu Wai Hospital, Beijing, China
- Target Recruit Count
- 292
- Registration Number
- NCT06088433
- Locations
- 🇨🇳
Fuwai Hospital, Beijing, Beijing, China
POPular GUILTY PILOT: Genotype-guided Clopidogrel Monotherapy
- Conditions
- Interventions
- First Posted Date
- 2023-07-03
- Last Posted Date
- 2024-12-03
- Lead Sponsor
- St. Antonius Hospital
- Target Recruit Count
- 200
- Registration Number
- NCT05926271
- Locations
- 🇳🇱
St. Antonius Hospital, Nieuwegein, Utrecht, Netherlands
Drug Development Updates
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