Clopidogrel
- Generic Name
- Clopidogrel
- Brand Names
- Duoplavin, Plavix, Zyllt, Clopidogrel BGR (previously Zylagren), Clopidogrel TAD, Clopidogrel ratiopharm, Clopidogrel Zentiva (previously Clopidogrel Winthrop), Clopidogrel Krka, Clopidogrel Krka d.d. (previously Zopya), Clopidogrel Teva (hydrogen sulphate), Clopidogrel HCS, Iscover, Grepid, Clopidogrel Taw Pharma (previously Clopidogrel Mylan), Clopidogrel Viatris (previously Clopidogrel Taw Pharma)
- Drug Type
- Small Molecule
- Chemical Formula
- C16H16ClNO2S
- CAS Number
- 113665-84-2
- Unique Ingredient Identifier
- A74586SNO7
- Background
Clopidogrel is a prodrug of a platelet inhibitor used to reduce the risk of myocardial infarction and stroke. Clopidogrel is indicated to reduce the risk of myocardial infarction for patients with non-ST elevated acute coronary syndrome (ACS), patients with ST-elevated myocardial infarction, and in recent MI, stroke, or established peripheral arterial diseas...
- Indication
1.用于新近心肌梗死、新近脑卒中或确诊的周围动脉病变患者，可减少新的缺血性脑卒中、心肌梗死和死亡等心脑血管事件的符合终点；
2.用于急性冠状动脉综合征（不稳定心绞痛和非ST段抬高心肌梗死）患者；
3.用于冠状动脉支架置入术后预防支架内血栓形成（与阿司匹林联用）。
- Associated Conditions
- Acute Coronary Syndrome (ACS), Acute Myocardial Infarction (AMI), Cardiovascular Events, Atherothrombotic events
- Associated Therapies
- -
A Study on BMS-986177 for the Prevention of a Stroke in Patients Receiving Aspirin and Clopidogrel
- Conditions
- Interventions
- First Posted Date
- 2018-12-06
- Last Posted Date
- 2023-06-12
- Lead Sponsor
- Bristol-Myers Squibb
- Target Recruit Count
- 2366
- Registration Number
- NCT03766581
- Locations
- 🇺🇸
Temple University Hospital, Philadelphia, Pennsylvania, United States
🇺🇸Local Institution - 0019, York, Pennsylvania, United States
🇺🇸Neurology Consultants of Dallas, PA, Dallas, Texas, United States
A Study to Assess Administration of an Oral Anti-thrombotic With Antiplatelet Therapy in Healthy Subjects
- Conditions
- Interventions
- First Posted Date
- 2018-10-09
- Last Posted Date
- 2021-09-29
- Lead Sponsor
- Bristol-Myers Squibb
- Target Recruit Count
- 113
- Registration Number
- NCT03698513
- Locations
- 🇺🇸
PPD Development, LP, Austin, Texas, United States
Low-dose of Ticagrelor and Standard-dose Clopidogrel on Platelet Effects in Chinese Patients With Stable CAD.
- Conditions
- Interventions
- First Posted Date
- 2018-09-20
- Last Posted Date
- 2021-12-21
- Target Recruit Count
- 36
- Registration Number
- NCT03679091
- Locations
- 🇨🇳
VerifyNow, Harbin, California, China
clOpidogrel "resIstaNce" in a Selected Population of Patients at a Tertiary Cardiovascular Center in Trinidad
- Conditions
- First Posted Date
- 2018-09-12
- Last Posted Date
- 2018-09-27
- Lead Sponsor
- The University of The West Indies
- Target Recruit Count
- 40
- Registration Number
- NCT03667066
- Locations
- 🇹🇹
Eric Williams Medical Sciences Complex, Port Of Spain, North, Trinidad and Tobago
Effect of Diabetes and Hepatic Enzymes Mutation on Clopidogrel VS Ticagrelor Activity in Myocardial Infarction (MI) Patients Undergoing Primary Percutaneous Coronary Intervention (PCI)
- First Posted Date
- 2018-08-03
- Last Posted Date
- 2019-01-14
- Lead Sponsor
- Cairo University
- Target Recruit Count
- 1022
- Registration Number
- NCT03613857
- Locations
- 🇪🇬
Faculty of pharmacy Cairo university, Cairo, Egypt
Comparison of Two Different Antiplatelet Preparations for an Unruptured Intracranial Aneurysm
- Conditions
- Interventions
- First Posted Date
- 2018-07-10
- Last Posted Date
- 2022-04-27
- Lead Sponsor
- Seoul National University Hospital
- Target Recruit Count
- 198
- Registration Number
- NCT03581409
- Locations
- 🇰🇷
Seoul National Univeristy Bundang Hospital, Seongnam-si, Gyeonggi-do, Korea, Republic of
A Clinical Study to Assess the Effect of Clopidogrel on the Pharmacokinetics of Selexipag and Its Active Metabolite in Healthy Male Subjects
- First Posted Date
- 2018-04-12
- Last Posted Date
- 2018-06-01
- Lead Sponsor
- Actelion
- Target Recruit Count
- 22
- Registration Number
- NCT03496506
- Locations
- 🇧🇪
Clinical Pharmacology Unit (CPU), Merksem, Belgium
Left Atrial Appendage CLOSURE in Patients With Atrial Fibrillation Compared to Medical Therapy
- First Posted Date
- 2018-03-13
- Last Posted Date
- 2021-07-30
- Lead Sponsor
- Charite University, Berlin, Germany
- Target Recruit Count
- 1512
- Registration Number
- NCT03463317
- Locations
- 🇩🇪
Vivantes Klinik Am Urban, Kardiologie, Berlin, Germany
🇩🇪Charité Universitätsmedizin Berlin, CBF, Kardiologie, Berlin, Germany
🇩🇪Vivantes Klinikum Neukölln, Kardiologie, Berlin, Germany
Low Maintenance Dose Ticagrelor Versus Clopidogrel in Diabetes Patients Undergoing PCI
- Conditions
- Interventions
- First Posted Date
- 2018-02-19
- Last Posted Date
- 2021-11-30
- Lead Sponsor
- University of Florida
- Target Recruit Count
- 40
- Registration Number
- NCT03437044
- Locations
- 🇺🇸
University of Florida, Jacksonville, Florida, United States
A Study to Investigate the Interaction Between ACT-246475 and Clopidogrel, Prasugrel, and Ticagrelor in Healthy Subjects
- Conditions
- Interventions
- First Posted Date
- 2018-02-13
- Last Posted Date
- 2022-11-16
- Lead Sponsor
- Idorsia Pharmaceuticals Ltd.
- Target Recruit Count
- 77
- Registration Number
- NCT03430661
- Locations
- 🇺🇸
Biotrial Inc, Newark, New Jersey, United States
Drug Development Updates
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