Midodrine
- Generic Name
- Midodrine
- Brand Names
- Proamatine
- Drug Type
- Small Molecule
- Chemical Formula
- C12H18N2O4
- CAS Number
- 42794-76-3
- Unique Ingredient Identifier
- 6YE7PBM15H
- Background
An ethanolamine derivative that is an adrenergic alpha agonist. It is used as a vasoconstrictor agent in the treatment of hypotension.
- Indication
For the treatment of symptomatic orthostatic hypotension (OH).
- Associated Conditions
- Symptomatic Orthostatic Hypotension
- Associated Therapies
- -
Minimization of Intradialytic Hypotension Using Cardiography-Guided Intervention
- Conditions
- Interventions
- First Posted Date
- 2017-03-15
- Last Posted Date
- 2017-03-15
- Lead Sponsor
- Nimedical
- Target Recruit Count
- 35
- Registration Number
- NCT03080441
Midodrine in the Recovery Phase of Septic Shock
- First Posted Date
- 2016-12-13
- Last Posted Date
- 2024-01-11
- Lead Sponsor
- University of Virginia
- Registration Number
- NCT02990546
- Locations
- 🇺🇸
University of Virginia, Charlottesville, Virginia, United States
Effects of Midodrine and Droxidopa on Splanchnic Capacitance in Autonomic Failure
- Conditions
- Interventions
- First Posted Date
- 2016-09-12
- Last Posted Date
- 2024-12-12
- Lead Sponsor
- Vanderbilt University Medical Center
- Target Recruit Count
- 34
- Registration Number
- NCT02897063
- Locations
- 🇺🇸
Autonomic Dysfunction Center/ Vanderbilt University Medical Center, Nashville, Tennessee, United States
Midodrine During Recovery From Septic Shock
- First Posted Date
- 2016-05-12
- Last Posted Date
- 2017-11-06
- Lead Sponsor
- Northwell Health
- Registration Number
- NCT02771158
Hemodynamic Mechanisms of Abdominal Compression in the Treatment of Orthostatic Hypotension in Autonomic Failure
- First Posted Date
- 2015-04-29
- Last Posted Date
- 2024-03-26
- Lead Sponsor
- Vanderbilt University Medical Center
- Target Recruit Count
- 29
- Registration Number
- NCT02429557
- Locations
- 🇺🇸
Vanderbilt University, Nashville, Tennessee, United States
Midodrine for Ischemic Stroke With Penumbra
- First Posted Date
- 2015-03-09
- Last Posted Date
- 2017-05-17
- Lead Sponsor
- University of Utah
- Registration Number
- NCT02383121
- Locations
- 🇺🇸
University of Utah, Salt Lake City, Utah, United States
Treatment of Orthostatic Intolerance in Patients With Parkinson's Disease Using Midodrine
- First Posted Date
- 2015-02-18
- Last Posted Date
- 2015-08-26
- Lead Sponsor
- Corporal Michael J. Crescenz VA Medical Center
- Target Recruit Count
- 50
- Registration Number
- NCT02365012
- Locations
- 🇺🇸
PVAMC, Philadelphia, Pennsylvania, United States
Treatment and Prognosis of Neurogenic Orthostatic Hypotension : A Prospective Randomized Study
- Conditions
- Interventions
- First Posted Date
- 2014-12-04
- Last Posted Date
- 2021-10-19
- Lead Sponsor
- Seoul National University Hospital
- Target Recruit Count
- 87
- Registration Number
- NCT02308124
- Locations
- 🇰🇷
Seoul National University Hospital, Seoul, Korea, Republic of
Blood Pressure, Cerebral Blood Flow and Cognition in Spinal Cord Injury
- First Posted Date
- 2014-12-04
- Last Posted Date
- 2023-06-28
- Lead Sponsor
- James J. Peters Veterans Affairs Medical Center
- Target Recruit Count
- 60
- Registration Number
- NCT02307565
- Locations
- 🇺🇸
James J Peters VAMC, Bronx, New York, United States
🇺🇸Kessler Foundation Research Center, West Orange, New Jersey, United States
Role of Midodrine and Tolvaptan in Patients With Cirrhosis With Refractory or Recurrent Ascites
- Conditions
- Interventions
- First Posted Date
- 2014-06-24
- Last Posted Date
- 2017-09-19
- Target Recruit Count
- 50
- Registration Number
- NCT02173288
- Locations
- 🇮🇳
Dept. of Hepatology, PGIMER, Chandigarh, Chandigarh, India
Drug Development Updates
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