Misoprostol
- Generic Name
- Misoprostol
- Brand Names
- Arthrotec, Cytotec, Mifegymiso
- Drug Type
- Small Molecule
- Chemical Formula
- C22H38O5
- CAS Number
- 59122-46-2
- Unique Ingredient Identifier
- 0E43V0BB57
- Background
Misoprostol is a prostaglandin analog used to reduce the risk of NSAID related ulcers, manage miscarriages, prevent post partum hemorrhage, and also for first trimester abortions. The stimulation of prostaglandin receptors in the stomach reduces gastric acid secretion, while stimulating these receptors in the uterus and cervix can increase the strength and f...
- Indication
Misoprostol is indicated as a tablet to reduce the risk of NSAID induced gastric ulcers but not duodenal ulcers in high risk patients. Misoprostol is also formulated in combination with diclofenac to treat symptoms of osteoarthritis or rheumatoid arthritis in patients with a high risk of developing gastric ulcers. Misoprostol is used off label for the manage...
- Associated Conditions
- Gastric Ulcer, Incomplete Abortion, Missed Abortion, Postpartum Haemorrhage (PPH)
- Associated Therapies
- Induction of cervix ripening therapy, Medically induced abortion
Use Misoprostol to Optimize Prevention of Cervical Cancer
- Conditions
- Interventions
- First Posted Date
- 2024-11-01
- Last Posted Date
- 2024-12-05
- Lead Sponsor
- University of Alabama at Birmingham
- Target Recruit Count
- 420
- Registration Number
- NCT06669533
- Locations
- 🇨🇲
Cameroon Baptist Convention Health Core, EtougEbe Baptist Hospital Yaoundé, Yaoundé, Center Region, Cameroon
Mifepristone vs Misoprostol
- First Posted Date
- 2024-07-16
- Last Posted Date
- 2024-11-08
- Lead Sponsor
- Montefiore Medical Center
- Target Recruit Count
- 94
- Registration Number
- NCT06502158
- Locations
- 🇺🇸
Montefiore Medical Center, Bronx, New York, United States
Letrozole and Misoprostol for Early Pregnancy Loss Management
- Conditions
- Interventions
- First Posted Date
- 2024-06-11
- Last Posted Date
- 2024-08-29
- Lead Sponsor
- University of Pennsylvania
- Target Recruit Count
- 30
- Registration Number
- NCT06452719
- Locations
- 🇺🇸
PEACE / Penn Medicine, Philadelphia, Pennsylvania, United States
Comparative Study Between the Roles of Intrauterine Misoprostol Versus the Sublingual Route for Prevention of Postpartum Blood Loss in Elective Cesarean Sections
- First Posted Date
- 2024-04-15
- Last Posted Date
- 2024-04-15
- Lead Sponsor
- Cairo University
- Target Recruit Count
- 192
- Registration Number
- NCT06364098
- Locations
- 🇪🇬
Faculty of medicine, Kasr Alainy, Cairo, Al Manyal, Egypt
Evaluation of Telemedicine Medical Abortion Service in Ecuador
- First Posted Date
- 2024-02-21
- Last Posted Date
- 2024-10-15
- Lead Sponsor
- Gynuity Health Projects
- Target Recruit Count
- 100
- Registration Number
- NCT06270056
- Locations
- 🇪🇨
El Comité de Derechos Sexuales y Reproductivos de Ecuador (CODESER), Ambato, Ecuador
🇪🇨Cemoplaf, Quito, Ecuador
🇪🇨Federación Nacional de Obstetrices y Obstetras del Ecuador (FENOE), Quito, Ecuador
Different Medications to Induce Labor
- First Posted Date
- 2024-02-14
- Last Posted Date
- 2024-08-05
- Lead Sponsor
- Icahn School of Medicine at Mount Sinai
- Target Recruit Count
- 300
- Registration Number
- NCT06259097
- Locations
- 🇺🇸
Mount Sinai Hospital, New York, New York, United States
Induction of Labor in Morbidly Obese Patients
- First Posted Date
- 2024-01-10
- Last Posted Date
- 2024-08-16
- Lead Sponsor
- University of Maryland, Baltimore
- Target Recruit Count
- 162
- Registration Number
- NCT06199154
- Locations
- 🇺🇸
University of Maryland Medical Center, Baltimore, Maryland, United States
Effect of Maternal Age and BMI on Induction of Labor Using Oral Misoprostol in Late-term Pregnancies: a Retrospective Cross-sectional Study
- Conditions
- First Posted Date
- 2023-12-28
- Last Posted Date
- 2023-12-28
- Lead Sponsor
- University of Palermo
- Target Recruit Count
- 104
- Registration Number
- NCT06184139
- Locations
- 🇮🇹
Andrea Etrusco, Palermo, Italy
Comparative Study Between Preoperative and Postoperative Rectal Misoprostol
- Conditions
- Interventions
- First Posted Date
- 2023-09-21
- Last Posted Date
- 2024-08-20
- Lead Sponsor
- Egymedicalpedia
- Target Recruit Count
- 128
- Registration Number
- NCT06049160
- Locations
- 🇪🇬
Faculty of medicine, Cairo University, Cairo, Egypt
Methods Decreasing Bleeding in Open Myomectomy
- Conditions
- Interventions
- First Posted Date
- 2023-04-10
- Last Posted Date
- 2023-04-10
- Lead Sponsor
- Cairo University
- Target Recruit Count
- 105
- Registration Number
- NCT05806307
- Locations
- 🇪🇬
faculty of medicine, Kasr el ainy hospital, Cairo university, Cairo, Egypt
Drug Development Updates
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