Aripiprazole

Generic Name
Aripiprazole
Brand Names
Abilify, Aripiprazole Mylan Pharma (previously Aripiprazole Pharmathen), Abilify Maintena, Aripiprazole Accord, Aripiprazole Sandoz, Aripiprazole Zentiva
Drug Type
Small Molecule
Chemical Formula
C23H27Cl2N3O2
CAS Number
129722-12-9
Unique Ingredient Identifier
82VFR53I78
Background

Aripiprazole is an atypical antipsychotic orally indicated for the treatment of schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and Tourette's. It is also indicated as an injection for agitation associated with schizophrenia or bipolar mania. Aripiprazole exerts its effects through agonism of dopaminergic and 5-HT1A ...

Indication

Aripiprazole is indicated for the treatment of acute manic and mixed episodes associated with bipolar I disorder, irritability associated with autism spectrum disorder, schizophrenia, and Tourette's disorder. It is also used as an adjunctive treatment of major depressive disorder.[L45859 An injectable formulation of aripiprazole is indicated for agitation as...

Associated Conditions
Agitation, Bipolar 1 Disorder, Irritability, Major Depressive Disorder (MDD), Mixed manic depressive episode, Psychosis, Psychotic Depression, Schizophrenia, Tourette's Disorder (TD), Acute Manic episode
Associated Therapies
Monotherapy

Pharmacovigilance in Gerontopsychiatric Patients

Phase 3
Terminated
Conditions
Interventions
Drug: Phenobarbital
Drug: Phenytoin
Drug: Carbamazepine
Drug: Oxcarbazepine
Drug: Valproic Acid
Drug: Lamotrigine
Drug: Topiramate
Drug: Gabapentin
Drug: Levetiracetam
Drug: Pregabalin
Drug: Lacosamide
Drug: Clonazepam
Drug: Biperiden
Drug: Levomepromazine
Drug: Fluphenazine
Drug: Perphenazine
Drug: Perazine
Drug: Thioridazine
Drug: Haloperidol
Drug: Melperone
Drug: Pipamperone
Drug: Bromperidol
Drug: Benperidol
Drug: Sertindole
Drug: Ziprasidone
Drug: Flupentixol
Drug: Chlorprothixene
Drug: Zuclopenthixol
Drug: Fluspirilene
Drug: Pimozide
Drug: Clozapine
Drug: Olanzapine
Drug: Quetiapine
Drug: Sulpiride
Drug: Tiapride
Drug: Amisulpride
Drug: Prothipendyl
Drug: Risperidone
Drug: Aripiprazole
Drug: Paliperidone
Drug: Diazepam
Drug: Oxazepam
Drug: Lorazepam
Drug: Bromazepam
Drug: Clobazam
Drug: Alprazolam
Drug: Hydroxyzine
Drug: Buspirone
Drug: Chloral Hydrate
Drug: Flurazepam
Drug: Nitrazepam
Drug: Triazolam
Drug: Lormetazepam
Drug: Temazepam
Drug: Midazolam
Drug: Brotizolam
Drug: Zopiclone
Drug: Zolpidem
Drug: Zaleplon
Drug: Melatonin
Drug: Clomethiazole
Drug: Diphenhydramine
Drug: Promethazine
Drug: Imipramine
Drug: Clomipramine
Drug: Opipramol
Drug: Trimipramine
Drug: Amitriptyline
Drug: Nortriptyline
Drug: Doxepin
Drug: Maprotiline
Drug: Amitriptyline oxide
Drug: Fluoxetine
Drug: Citalopram
Drug: Paroxetine
Drug: Sertraline
Drug: Fluvoxamine
Drug: Escitalopram
Drug: Tranylcypromine
Drug: Moclobemide
Drug: Mianserin
Drug: Trazodone
Drug: Mirtazapine
Drug: Bupropion
Drug: Venlafaxine
Drug: Reboxetine
Drug: Duloxetine
Drug: Agomelatine
Drug: Pyritinol
Drug: Piracetam
Drug: Donepezil
Drug: Rivastigmine
Drug: Galantamine
Drug: Memantine
Drug: Nicergoline
Drug: Acamprosate
Drug: Lithium
First Posted Date
2015-03-02
Last Posted Date
2018-02-28
Lead Sponsor
Hannover Medical School
Target Recruit Count
407
Registration Number
NCT02374567
Locations
🇩🇪

Bezirkskrankenhaus Augsburg, Augsburg, Germany

🇩🇪

Krankenhaus Hedwigshöhe, Berlin, Germany

🇩🇪

Hannover Medical School, Hannover, Germany

and more 2 locations

Fluoxetine vs Aripiprazole Comparative Trial (FACT)

First Posted Date
2015-02-06
Last Posted Date
2023-11-15
Lead Sponsor
Northwell Health
Target Recruit Count
9
Registration Number
NCT02357849
Locations
🇺🇸

The Zucker Hillside Hospital, Glen Oaks, New York, United States

Pan European Collaboration on Antipsychotic Naïve Schizophrenia II

Phase 4
Completed
Conditions
Interventions
First Posted Date
2015-01-16
Last Posted Date
2021-04-28
Lead Sponsor
University of Copenhagen
Target Recruit Count
130
Registration Number
NCT02339844
Locations
🇩🇰

Center for Neuropsychiatric Schizophrenia Research, University of Copenhagen, Psychiatric Centre Glostrup, Copenhagen, Glostrup, Denmark

Comparison of Aripiprazole Versus Risperidone on Brain Morphology Using MRI

First Posted Date
2015-01-08
Last Posted Date
2016-06-01
Lead Sponsor
University of British Columbia
Target Recruit Count
60
Registration Number
NCT02334904
Locations
🇨🇦

BC Mental Health & Addictions Research Institute, Vancouver, British Columbia, Canada

Comparative Study of Aripiprazole, Quetiapine and Ziprasidone in the Treatment of First Episode Nonaffective Psychosis

First Posted Date
2014-12-03
Last Posted Date
2017-03-14
Lead Sponsor
Fundación Marques de Valdecilla
Target Recruit Count
203
Registration Number
NCT02305823
Locations
🇪🇸

University Hospital Marques de Valdecilla, Santander, Cantabria, Spain

European Long-acting Antipsychotics in Schizophrenia Trial

First Posted Date
2014-05-26
Last Posted Date
2020-09-01
Lead Sponsor
UMC Utrecht
Target Recruit Count
536
Registration Number
NCT02146547
Locations
🇧🇪

ZNA, department of Psychiatry, locatie Stuivenberg, Antwerp, Lange Beeldekensstraat 267, Belgium

🇷🇴

Sitalul Clinic Judetean Mures, Targu Mureş, Romania

🇧🇬

University Hospital of Neurology and Psychiatry 'St. Naum' 1, Sofia, Louben Roussev Str., Bulgaria

and more 46 locations

Antipsychotic to Treat Psychosis Syndrome

First Posted Date
2014-05-14
Last Posted Date
2014-05-14
Lead Sponsor
Central South University
Target Recruit Count
300
Registration Number
NCT02137616
Locations
🇨🇳

the Second Xiangya Hospital, Changsha, Hunan, China

Study to Evaluate the Efficacy and Safety of Aripiprazole

Phase 4
Conditions
Interventions
First Posted Date
2014-02-24
Last Posted Date
2014-03-11
Lead Sponsor
Yoo-Sook Joung
Target Recruit Count
79
Registration Number
NCT02069977
Locations
🇰🇷

Samsung Medical Center, Seoul, Korea, Republic of

🇰🇷

Inje University Ilsan Paik Hospital, Ilsan, Gyeonggi-do, Korea, Republic of

🇵🇭

Medical City, Pasig, Philippines

and more 3 locations

Brexpiprazole (OPC-34712) Trial in the Treatment of Adults With Acute Schizophrenia

Phase 3
Completed
Conditions
Interventions
First Posted Date
2014-02-04
Last Posted Date
2015-12-30
Lead Sponsor
Otsuka Pharmaceutical Development & Commercialization, Inc.
Target Recruit Count
97
Registration Number
NCT02054702

Adjunctive Aripiprazole in the Treatment of Risperidone-Induced Hyperprolactinemia

Not Applicable
Conditions
Interventions
First Posted Date
2013-12-17
Last Posted Date
2013-12-17
Lead Sponsor
Beijing HuiLongGuan Hospital
Target Recruit Count
120
Registration Number
NCT02013232
Locations
🇨🇳

Beijing HuiLongGuan Hospital, Beijing, Beijing, China

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