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Aripiprazole

Generic Name
Aripiprazole
Brand Names
Abilify, Aripiprazole Mylan Pharma (previously Aripiprazole Pharmathen), Abilify Maintena, Aripiprazole Accord, Aripiprazole Sandoz, Aripiprazole Zentiva
Drug Type
Small Molecule
Chemical Formula
C23H27Cl2N3O2
CAS Number
129722-12-9
Unique Ingredient Identifier
82VFR53I78

Overview

Aripiprazole is an atypical antipsychotic orally indicated for the treatment of schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and Tourette's. It is also indicated as an injection for agitation associated with schizophrenia or bipolar mania. Aripiprazole exerts its effects through agonism of dopaminergic and 5-HT1A receptors and antagonism of alpha-adrenergic and 5-HT2A receptors. Aripiprazole was given FDA approval on November 15, 2002.

Background

Aripiprazole is an atypical antipsychotic orally indicated for the treatment of schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and Tourette's. It is also indicated as an injection for agitation associated with schizophrenia or bipolar mania. Aripiprazole exerts its effects through agonism of dopaminergic and 5-HT1A receptors and antagonism of alpha-adrenergic and 5-HT2A receptors. Aripiprazole was given FDA approval on November 15, 2002.

Indication

Aripiprazole is indicated for the treatment of acute manic and mixed episodes associated with bipolar I disorder, irritability associated with autism spectrum disorder, schizophrenia, and Tourette's disorder. It is also used as an adjunctive treatment of major depressive disorder.[L45859 An injectable formulation of aripiprazole is indicated for agitation associated with schizophrenia or bipolar mania. Finally, an extended-release, bimonthly injection formulation of aripiprazole is indicated for the treatment of adult schizophrenia and maintenance therapy for adult bipolar I disorder.

Associated Conditions

  • Agitation
  • Bipolar 1 Disorder
  • Irritability
  • Major Depressive Disorder (MDD)
  • Mixed manic depressive episode
  • Psychosis
  • Psychotic Depression
  • Schizophrenia
  • Tourette's Disorder (TD)
  • Acute Manic episode

FDA Approved Products

Aripiprazole
Manufacturer:Zydus Pharmaceuticals USA Inc.
Route:ORAL
Strength:15 mg in 1 1
Approved: 2023/05/02
NDC:68382-084
Aripiprazole
Manufacturer:Zydus Pharmaceuticals USA Inc.
Route:ORAL
Strength:20 mg in 1 1
Approved: 2023/05/02
NDC:68382-085
Aripiprazole
Manufacturer:Major Pharmaceuticals
Route:ORAL
Strength:15 mg in 1 1
Approved: 2023/10/11
NDC:0904-7369
Aripiprazole
Manufacturer:Major Pharmaceuticals
Route:ORAL
Strength:2 mg in 1 1
Approved: 2023/10/11
NDC:0904-7366
Aripiprazole
Manufacturer:A-S Medication Solutions
Route:ORAL
Strength:15 mg in 1 1
Approved: 2020/03/07
NDC:50090-4817

Singapore Approved Products

No Singapore products found for this drug

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