Overview
Octinoxate is a cinnamate ester and common ingredient in sunscreen and other skin care products to minimize DNA photodamage. It was originally developed in 1950's as an organic UV-B filter that absorbs UV-B rays from sun. It is often combined with nanoparticles or other water-resistant liposomes in formulations to increase the localization at the epidermis and decrease the risk of percutaneous absorption. Its use in pharmaceutical and cosmetic formulations is approved by FDA.
Indication
As an active ingredient in sunscreens and lip balms. Used for protection against damaging effects of sun rays.
Associated Conditions
- Sunburn
Clinical Trials
Title | Posted | Study ID | Phase | Status | Sponsor |
|---|
No clinical trials found
No clinical trials found for this drug
FDA Drug Approvals
Approved Product | Manufacturer | NDC Code | Route | Strength | Effective Date |
|---|---|---|---|---|---|
| Andalou naturals | 55560-0107 | TOPICAL | 70 mg in 1 mL | 6/9/2025 | |
| OraLabs | 63645-176 | TOPICAL | 20 mg in 1 g | 4/28/2025 | |
| The Mentholatum Company | 10742-8745 | TOPICAL | 75 mg in 1 g | 5/2/2025 | |
| CA-Botana International | 35192-033 | TOPICAL | 10.62 g in 141.7 g | 7/6/2025 | |
| CP Skin Health Group, Inc. | 72043-2500 | TOPICAL | 75 g in 1000 g | 3/31/2025 | |
| Conopco d/b/a/ Unilever | 64942-2354 | TOPICAL | 4 g in 100 mL | 3/27/2025 | |
| BEL STAR SA | 14141-324 | TOPICAL | 50 mg in 1 mL | 6/22/2025 | |
| SHISEIDO AMERICAS CORPORATION | 58411-913 | TOPICAL | 1.715 g in 35 mL | 5/21/2025 | |
| BEL STAR SA | 14141-405 | TOPICAL | 30 mg in 1 mL | 4/28/2025 | |
| SHISEIDO AMERICAS CORPORATION | 58411-918 | TOPICAL | 1.715 g in 35 mL | 5/21/2025 |
EMA Drug Approvals
Approved Product | Authorization Holder | Status | Issued Date |
|---|---|---|---|
| No EMA approvals found for this drug. | |||
HSA Drug Approvals
Approved Product | Manufacturer | Approval Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| No HSA approvals found for this drug. | |||||
NMPA Drug Approvals
Approved Product | Company | Approval Number | Drug Type | Dosage Form | Approval Date |
|---|---|---|---|---|---|
| No NMPA approvals found for this drug. | |||||
PPB Drug Approvals
Approved Product | Registration No. | Company | Licence No. | Strength | Registration Date |
|---|---|---|---|---|---|
| No PPB approvals found for this drug. | |||||
TGA Drug Approvals
Approved Product | ARTG ID | Sponsor | Registration Type | Status | Registration Date |
|---|---|---|---|---|---|
| Cetaphil Sun Ultra-Light Lotion SPF50+ Body & Face | 286720 | Medicine | A | 3/14/2017 | |
| Mesoestetic Light Water Antiaging Veil Mesoprotech | 316427 | Medicine | A | 4/12/2019 | |
| QV FACE MOISTURISING DAY CREAM SPF 30 | 374097 | Medicine | A | 9/2/2021 | |
| Sun Zapper Blue SPF50+ Zinc Stick | 279799 | Medicine | A | 8/31/2016 | |
| Sun Zapper Extreme Zinc SPF 50+ Orange Sun | 391736 | Medicine | A | 7/4/2022 | |
| Active Face Great SPF50+ lotion | 439830 | Medicine | A | 2/5/2024 | |
| Sun Zapper SPF 50+ Yellow Zinc Stick | 487211 | Medicine | A | 4/30/2025 | |
| ASHANTI LIP PROTECTION OINTMENT SPF 30+ tube | 91788 | Ashanti Ostrich Oil Pty Ltd | Medicine | A | 11/13/2002 |
| Sun Zapper Yellow SPF50+ Zinc Stick | 282968 | Medicine | A | 11/28/2016 | |
| Facesaver Great SPF50+ Lotion | 386992 | Medicine | A | 4/12/2022 |
Health Canada Drug Approvals
Approved Product | Company | DIN | Dosage Form | Strength | Market Date |
|---|---|---|---|---|---|
| OIL OF OLAY DAILY UV PROTECTANT MOIST CRM | procter & gamble inc | 01947400 | Cream - Topical | 7.5 % | 12/31/1992 |
| BODY ZONE SPF 8 SUNSCREEN | Biotech Holdings Ltd. | 02237975 | Lotion - Topical | 7.5 % | 6/15/1998 |
| BOBBI BROWN MOISTURE RICH FOUNDATION SPF 15 | dist. bobbi brown professional cosmetics | 02243385 | Emulsion - Topical | 2.23 % | 6/1/2001 |
| OLAY COMPLETE 30 UVA/UVB 365 DAILY MOISTURIZING LOTION WITH SPF BROAD SPECTRUM SPF 30 SENSITIVE | procter & gamble inc | 02461188 | Lotion - Topical | 7.5 % / W/W | 1/1/2018 |
| SHISEIDO TANNING FACE CRM SPF 4 | shiseido america inc | 02024020 | Cream - Topical | 4 % | 12/31/1994 |
| MARCELLE HYDRA-C 24 H + SPF 15 FPS MOISTURIZING CREAM CRÈME HYDRATANTE DRY SKIN PEAUX SÈCHES | groupe marcelle inc | 02434768 | Cream - Topical | 7.5 % / W/W | 11/3/2015 |
| LUMINOUS MOISTURIZING FOUNDATION SPF 15 | act cosmetics america inc | 02463342 | Lotion - Topical | 0.9 % / W/W | N/A |
| CELLULAR DEFENSE SHIELD SPF 15 | la prairie inc. | 02235041 | Liquid - Topical | 7.5 % | 5/31/1999 |
| MARCELLE CITY HIGH PROTECTION URBAN DAY CREAM SOIN JOUR HAUTE PROTECTION URBAINE SPF 30 FPS | groupe marcelle inc | 02464721 | Cream - Topical | 7.5 % / W/W | 12/7/2017 |
| SEA & SKI SPF 30 SPORT SUNBLOCK | faulding consumer, inc. | 02244388 | Lotion - Topical | 6 % | 3/5/2002 |
CIMA AEMPS Drug Approvals
Approved Product | Company | Registration Number | Pharmaceutical Form | Prescription Type | Status |
|---|---|---|---|---|---|
| No CIMA AEMPS (Spain) approvals found for this drug. | |||||
Philippines FDA Drug Approvals
Approved Product | Company | License Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| No Philippines FDA approvals found for this drug. | |||||
Saudi SFDA Drug Approvals
Approved Product | Company | License Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| No Saudi SFDA approvals found for this drug. | |||||
Malaysia NPRA Drug Approvals
Approved Product | Company | Registration Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| No Malaysia NPRA approvals found for this drug. | |||||
UK EMC Drug Information
Medicine Name | MA Holder | MA Number | Pharmaceutical Form | Active Ingredient | Authorization Date |
|---|---|---|---|---|---|
| No UK EMC drug information found for this drug. | |||||
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