MedPath

Sasanlimab

Generic Name
Sasanlimab

A Clinical Trial of PF-08046037 Alone or With Sasanlimab in Patients With Advanced or Metastatic Malignancies

Phase 1
Not yet recruiting
Conditions
Carcinoma, Non Small Cell Lung
Squamous Cell Carcinoma of the Head and Neck (SCCHN)
Carcinoma, Pancreatic Ductal
Malignant Melanoma
Interventions
First Posted Date
2025-05-16
Last Posted Date
2025-05-16
Lead Sponsor
Pfizer
Target Recruit Count
399
Registration Number
NCT06974734
Locations
🇺🇸

START Midwest, Grand Rapids, Michigan, United States

A Study to Learn About the Study Medicine Called PF-08046032 in People With Advanced Cancers.

Phase 1
Recruiting
Conditions
Peripheral T Cell Lymphoma
Diffuse Large B-cell Lymphoma
Classical Hodgkin Lymphoma
Head and Neck Squamous Cell Carcinoma
Melanoma
Non-Small Cell Lung Cancer
Interventions
First Posted Date
2025-03-11
Last Posted Date
2025-05-20
Lead Sponsor
Pfizer
Target Recruit Count
220
Registration Number
NCT06870487
Locations
🇺🇸

Fred Hutchinson Cancer Center., Seattle, Washington, United States

🇺🇸

University of Washington Medical Center- Montlake, Seattle, Washington, United States

🇺🇸

NEXT Oncology, San Antonio, Texas, United States

A Study to Learn About PF-07921585 Alone or With Other Anti-cancer Medicines in People With Cancer

Phase 1
Active, not recruiting
Conditions
Non Small Cell Lung Cancer
Bladder Cancer
Renal Cell Carcinoma
Head and Neck Cancer
Melanoma
Colorectal Cancer
Interventions
First Posted Date
2024-08-30
Last Posted Date
2025-04-20
Lead Sponsor
Pfizer
Target Recruit Count
4
Registration Number
NCT06580938
Locations
🇺🇸

Presbyterian/St. Lukes Medical Center, Denver, Colorado, United States

🇺🇸

Sarah Cannon Research Institute at HealthONE, Denver, Colorado, United States

🇺🇸

Highlands Oncology Group, Springdale, Arkansas, United States

and more 3 locations

A Study to Learn About How Different Amounts of the Study Medicine PF-07826390 Act in the Body of People With Cancer When Taken Alone or With Other Anti-cancer Medicines.

Phase 1
Active, not recruiting
Conditions
Colorectal Carcinoma
Squamous Cell Carcinoma of the Head and Neck
Renal Cell Carcinoma
Ovarian Carcinoma
Neoplasms
Non-small-cell Lung Cancer
Interventions
Other: SOC (anti-PD-1 + platinum -based chemo)
First Posted Date
2024-08-09
Last Posted Date
2025-04-06
Lead Sponsor
Pfizer
Target Recruit Count
5
Registration Number
NCT06546553
Locations
🇺🇸

START Midwest, Grand Rapids, Michigan, United States

🇺🇸

Thomas Jefferson University Honickman Center, Philadelphia, Pennsylvania, United States

🇺🇸

Thomas Jefferson University, Bodine Center for Radiation Therapy, Philadelphia, Pennsylvania, United States

and more 8 locations

A Study in Advanced/Metastatic Solid Tumors With the Study Medicine (PF-07329640) When Given Alone or In Combination

Phase 1
Terminated
Conditions
Advanced or Metastatic Solid Tumors
Colorectal Cancer
Non-Small Cell Lung Cancer
Urothelial Cancer
Melanoma
Interventions
First Posted Date
2024-06-07
Last Posted Date
2024-11-06
Lead Sponsor
Pfizer
Target Recruit Count
4
Registration Number
NCT06448364
Locations
🇵🇷

Hospital Oncológico Dr. Isaac González-Martinez, Rio Piedras, Puerto Rico

🇺🇸

NEXT Oncology, San Antonio, Texas, United States

🇵🇷

Pan American Center for Oncology Trials, LLC, Rio Piedras, Puerto Rico

and more 3 locations

A Study of PF-07820435 as a Single Agent and in Combination in Participants With Advanced Solid Tumors

Phase 1
Terminated
Conditions
Melanoma
Urothelial Carcinoma
Colorectal Carcinoma
Neoplasms
Non-small-cell Lung Cancer
Squamous Cell Carcinoma of the Head and Neck
Renal Cell Carcinoma
Ovarian Carcinoma
Interventions
First Posted Date
2024-02-29
Last Posted Date
2025-03-13
Lead Sponsor
Pfizer
Target Recruit Count
9
Registration Number
NCT06285097
Locations
🇺🇸

Florida Cancer Specialists Sarasota Drug Development Unit, Sarasota, Florida, United States

🇺🇸

Corewell Health (reference non-engagement letter), Grand Rapids, Michigan, United States

🇺🇸

START Midwest, Grand Rapids, Michigan, United States

and more 7 locations

Immuno-pet IMaging ResPonses AdministeRed Immune CheckpoiNt InhibiTor

Phase 2
Not yet recruiting
Conditions
NSCLC
Interventions
Drug: [89Zr]Zr-crefmirlimab berdoxam
Radiation: non-ablative radiotherapy
First Posted Date
2024-01-23
Last Posted Date
2024-11-29
Lead Sponsor
Radboud University Medical Center
Target Recruit Count
20
Registration Number
NCT06218069
Locations
🇳🇱

Radboud University Medical Center (Radboudumc), Nijmegen, Gelderland, Netherlands

🇩🇪

Eberhard Karls Universitaet Tuebingen (EKUT), Tuebingen, Germany

Ketohexokinase Inhibition in Hereditary Fructose Intolerance

Phase 2
Completed
Conditions
HFI
Interventions
First Posted Date
2023-10-18
Last Posted Date
2024-01-24
Lead Sponsor
Maastricht University Medical Center
Target Recruit Count
8
Registration Number
NCT06089265
Locations
🇳🇱

Maastricht University Medical centre, Maastricht, Limburg, Netherlands

Palbociclib and Sasanlimab for the Treatment of Advanced Clear Cell Renal Cell Carcinoma (ccRCC) or Papillary Renal Cell Carcinoma (pRCC)

Phase 1
Recruiting
Conditions
Papillary Renal Cell Carcinoma (Prcc)
Advanced Clear Cell Renal Carcinoma (Ccrcc)
Interventions
Drug: Palbocicilib
First Posted Date
2022-12-27
Last Posted Date
2025-03-10
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
100
Registration Number
NCT05665361
Locations
🇺🇸

National Institutes of Health Clinical Center, Bethesda, Maryland, United States

PF-07225570 Alone or in Combination With an Anti-PD-1 Antibody in Recurrent Non-muscle Invasive Bladder Cancer (NMIBC)

Phase 1
Withdrawn
Conditions
Bladder Cancer
Interventions
First Posted Date
2022-02-28
Last Posted Date
2023-03-08
Lead Sponsor
Pfizer
Registration Number
NCT05259397
Locations
🇵🇱

Szpital Specjalistyczny im. Sw. Rodziny SPZOZ, Warszawa, Poland

🇵🇱

Medical Concierge Centrum Medyczne, Warszawa, Poland

🇺🇸

Columbia University Medical Center - Herbert Irving Pavilion, New York, New York, United States

and more 1 locations
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