Epinephrine

Generic Name
Epinephrine
Brand Names
Adrenalin, Allerject, Anapen, Articadent, Astracaine, Auvi-Q, Citanest, Citanest Forte, Emerade, Epipen, Lignospan, Marcaine, Marcaine With Epinephrine, Octocaine, Octocaine With Epinephrine, Orabloc, Scandonest, Sensorcaine, Sensorcaine With Epinephrine, Septanest, Septocaine, Symjepi, Ultacan, Ultracaine, Vivacaine, Xylocaine, Xylocaine With Epinephrine, Zorcaine, Eurneffy
Drug Type
Small Molecule
Chemical Formula
C9H13NO3
CAS Number
51-43-4
Unique Ingredient Identifier
YKH834O4BH
Background

Epinephrine, also known as adrenaline, is a hormone and neurotransmitter and produced by the adrenal glands that can also be used as a drug due to its various important functions. Though it has long been used in the treatment of hypersensitivity reactions, epinephrine in the auto-injector form (EpiPen) has been available since 1987 in the USA. Many new produ...

Indication

Epinephrine injection is indicated in the emergency treatment of type I allergic reactions, including anaphylaxis. It is also used to increase mean arterial blood pressure in adult patients with hypotension associated with septic shock.
...

Associated Conditions
Anaphylaxis, Angioneurotic Edema, Bleeding, Bronchospasm, Complete Heart Block, Hypotension, Idiopathic Anaphylaxis, Laryngotracheobronchitis, Mild Intermittent Asthma, Nasal Congestion, Open Angle Glaucoma (OAG), Respiratory Distress, Severe Asthma, Syncope, Type I Hypersensitivity, Urticaria, Uterine Contractions, Ventricular Fibrillation, Resuscitation in cardiac arrest following anesthetic accidents, Severe hypersensitivity reactions, Unresponsive Asystole, Unresponsive Bradycardia
Associated Therapies
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Effects of Adrenaline Infiltration on Surgical Field of View in Endoscopic Sinus Surgery

Phase 4
Completed
Conditions
Interventions
First Posted Date
2023-05-22
Last Posted Date
2023-07-10
Lead Sponsor
Stanford University
Target Recruit Count
40
Registration Number
NCT05867342
Locations
🇺🇸

Stanford, Stanford, California, United States

Vasopressin vs. Epinephrine During Neonatal Cardiopulmonary Resuscitation

Phase 1
Recruiting
Conditions
Interventions
First Posted Date
2023-02-21
Last Posted Date
2023-11-30
Lead Sponsor
University of Alberta
Target Recruit Count
20
Registration Number
NCT05738148
Locations
🇨🇦

Royal Alexandra Hospital, Edmonton, Alberta, Canada

Lidocaine Irrigation in Shoulder Arthroscopy

First Posted Date
2022-11-22
Last Posted Date
2023-10-19
Lead Sponsor
Minia University
Target Recruit Count
50
Registration Number
NCT05624957
Locations
🇪🇬

Minia University Hospital, Minya, Egypt

The Effect of Epinephrine, Norepinephrine and Phenylephrine on Intraoperative Hemodynamic Performance

First Posted Date
2022-08-09
Last Posted Date
2022-10-19
Lead Sponsor
Medical University of Vienna
Target Recruit Count
225
Registration Number
NCT05492968
Locations
🇦🇹

Medical University of Vienna, Vienna, Austria

Opioid-Free Pain Protocol After Shoulder Arthroplasty

First Posted Date
2022-08-05
Last Posted Date
2024-01-12
Lead Sponsor
Henry Ford Health System
Target Recruit Count
80
Registration Number
NCT05488847
Locations
🇺🇸

Henry Ford Health, Detroit, Michigan, United States

Management of Acute Pulmonary Hypertensive Crisis in Children With Known Pulmonary Arterial Hypertension

First Posted Date
2022-06-30
Last Posted Date
2022-08-05
Lead Sponsor
Stanford University
Target Recruit Count
15
Registration Number
NCT05439460
Locations
🇺🇸

Cardiac Catheterization Lab,Stanford University Medical Center, Stanford, California, United States

Multi-Modal Anesthesia Protocol in Pain Management of Patients Undergoing Posterior Lumbar Spinal Fusion Surgery

First Posted Date
2022-06-10
Last Posted Date
2022-06-10
Lead Sponsor
University of Puerto Rico
Target Recruit Count
100
Registration Number
NCT05413902
Locations
🇵🇷

Puerto Rico Medical Center - University District Hospital, San Juan, Puerto Rico

Peri-Articular-Multimodal Drug and Oral Celecoxib in Management of Postoperative Pain of Total Knee Arthroplasty

First Posted Date
2022-04-13
Last Posted Date
2022-04-14
Lead Sponsor
Isfahan University of Medical Sciences
Target Recruit Count
146
Registration Number
NCT05324995
Locations
🇮🇷

Isfahan University of Medical Sciences, Isfahan, Iran, Islamic Republic of

Impact of Intracoronary Versus Intravenous Epinephrine Administration During Cardiac Arrest .

First Posted Date
2022-02-24
Last Posted Date
2022-08-16
Lead Sponsor
Lithuanian University of Health Sciences
Target Recruit Count
160
Registration Number
NCT05253937
Locations
🇱🇹

Ali Aldujeli, Kaunas, Lithuania

Comparison Between Levosimendan and Adrenaline in CABG Patients

Not Applicable
Conditions
Interventions
First Posted Date
2022-02-03
Last Posted Date
2022-02-08
Lead Sponsor
Assiut University
Target Recruit Count
52
Registration Number
NCT05222256
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