FN-1501
- Generic Name
- FN-1501
- Brand Names
- Cellcept, Myfenax, CellCept, Mycophenolate mofetil Teva, Myclausen
- Drug Type
- Small Molecule
- Chemical Formula
- C22H25N9O
- CAS Number
- 1429515-59-2
- Unique Ingredient Identifier
- 6MC966B505
- Background
Mycophenolate mofetil, also known as MMF or CellCept, is a prodrug of mycophenolic acid, and classified as a reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH). This drug is an immunosuppressant combined with drugs such as Cyclosporine and corticosteroids to prevent organ rejection after hepatic, renal, and cardiac transplants. It is markete...
- Indication
Mycophenolate mofetil is indicated in combination with other immunosuppressants to prevent the rejection of kidney, heart, or liver transplants in adult and pediatric patients ≥3 months old. Mycophenolate mofetil may also be used off-label as a second-line treatment for autoimmune hepatitis that has not responded adequately to first-line therapy. Other off-l...
- Associated Conditions
- Transplanted Organ Rejection
- Associated Therapies
- -
Pre-transplant Immunosuppression and Donor Stem Cell Transplant for the Treatment of Severe Hemoglobinopathies
- Conditions
- Interventions
- First Posted Date
- 2021-03-02
- Last Posted Date
- 2024-10-24
- Lead Sponsor
- M.D. Anderson Cancer Center
- Registration Number
- NCT04776850
A Single-arm Trial of Prophylactic Tocilizumab for Acute GVHD Prevention After Haploidentical HSCT.
- First Posted Date
- 2020-12-29
- Last Posted Date
- 2023-02-21
- Lead Sponsor
- Yi Luo
- Target Recruit Count
- 46
- Registration Number
- NCT04688021
- Locations
- 🇨🇳
The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China
PTCy and Ruxolitinib vs PTCy, Tacrolimus and MMF in MUD and Haploidentical HSCT
- Conditions
- Interventions
- First Posted Date
- 2020-12-16
- Last Posted Date
- 2024-05-07
- Lead Sponsor
- St. Petersburg State Pavlov Medical University
- Target Recruit Count
- 128
- Registration Number
- NCT04669210
- Locations
- 🇷🇺
National Hematology Research Center, Moscow, Russian Federation
🇷🇺RM Gorbacheva Research Institute, Saint Petersburg, Russian Federation
Cord Blood Transplant in Children and Young Adults With Blood Cancers and Non-malignant Disorders
- First Posted Date
- 2020-11-25
- Last Posted Date
- 2024-12-02
- Lead Sponsor
- Memorial Sloan Kettering Cancer Center
- Target Recruit Count
- 31
- Registration Number
- NCT04644016
- Locations
- 🇺🇸
Memorial Sloan Kettering Cancer Center, New York, New York, United States
A Study Comparing Haploidentical Hematopoietic Stem Cell Transplantations (HSCTs) From Young Non-first-degree and Older First-degree Donors in Hematological Malignancies
- First Posted Date
- 2020-09-14
- Last Posted Date
- 2023-02-21
- Lead Sponsor
- First Affiliated Hospital of Zhejiang University
- Target Recruit Count
- 160
- Registration Number
- NCT04547049
- Locations
- 🇨🇳
Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou, China
🇨🇳The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China
🇨🇳The Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China
Randomized Trial Evaluating Mycophenolate Mofetil in Children With Nephrotic Syndrome After Rituximab Treatment
- First Posted Date
- 2020-08-31
- Last Posted Date
- 2020-12-29
- Lead Sponsor
- Children's Hospital of Fudan University
- Registration Number
- NCT04531865
- Locations
- 🇨🇳
Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
🇨🇳Children's hospital of Fudan university, Shanghai, Shanghai, China
🇨🇳Shanghai Children's Hospital, Shanghai, China
Donor Stem Cell Transplant After Chemotherapy for the Treatment of Recurrent or Refractory High-Risk Solid Tumors in Pediatric and Adolescent-Young Adults
- Conditions
- Refractory Malignant Peripheral Nerve Sheath TumorEwing Sarcoma/Peripheral Primitive Neuroectodermal TumorRecurrent NeuroblastomaRecurrent RhabdomyosarcomaRefractory Malignant Solid NeoplasmDesmoplastic Small Round Cell TumorRecurrent Malignant Peripheral Nerve Sheath TumorRefractory Desmoplastic Small Round Cell TumorRecurrent Desmoplastic Small Round Cell TumorRecurrent Malignant Solid Neoplasm
- Interventions
- First Posted Date
- 2020-08-28
- Last Posted Date
- 2024-10-26
- Lead Sponsor
- M.D. Anderson Cancer Center
- Target Recruit Count
- 40
- Registration Number
- NCT04530487
- Locations
- 🇺🇸
M D Anderson Cancer Center, Houston, Texas, United States
Chemotherapy and Donor Stem Transplant for the Treatment of Patients With High Grade Brain Cancer
- Conditions
- Interventions
- First Posted Date
- 2020-08-21
- Last Posted Date
- 2024-10-26
- Lead Sponsor
- M.D. Anderson Cancer Center
- Registration Number
- NCT04521946
Belatacept in De Novo Heart Transplantation
- Conditions
- Interventions
- First Posted Date
- 2020-07-20
- Last Posted Date
- 2024-02-29
- Lead Sponsor
- NYU Langone Health
- Target Recruit Count
- 12
- Registration Number
- NCT04477629
- Locations
- 🇺🇸
NYU Langone Health, New York, New York, United States
🇺🇸Columbia University, New York, New York, United States
Mycophenolate Mofetil Combined With Radiation Therapy in Glioblastoma
- Conditions
- Interventions
- First Posted Date
- 2020-07-20
- Last Posted Date
- 2024-11-20
- Lead Sponsor
- University of Michigan Rogel Cancer Center
- Target Recruit Count
- 68
- Registration Number
- NCT04477200
- Locations
- 🇺🇸
University of Michigan Rogel Cancer Center, Ann Arbor, Michigan, United States
Drug Development Updates
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