Scopolamine
- Generic Name
- Scopolamine
- Brand Names
- Donnatal, Phenohytro, Transderm Scop
- Drug Type
- Small Molecule
- Chemical Formula
- C17H21NO4
- CAS Number
- 51-34-3
- Unique Ingredient Identifier
- DL48G20X8X
- Background
Scopolamine is a tropane alkaloid isolated from members of the Solanaceae family of plants, similar to atropine and hyoscyamine, all of which structurally mimic the natural neurotransmitter acetylcholine. Scopolamine was first synthesized in 1959, but to date, synthesis remains less efficient than extracting scopolamine from plants. As an acetylcholine analo...
- Indication
Scopolamine is indicated in adult patients for the prevention of nausea and vomiting associated with motion sickness and for the prevention of postoperative nausea and vomiting (PONV) associated with anesthesia or opiate analgesia.
- Associated Conditions
- Motion Sickness, Post Operative Nausea and Vomiting (PONV)
- Associated Therapies
- Anesthetic premedication therapy
Effects of Transdermal Scopolamine on Occupational Performance
- Conditions
- First Posted Date
- 2006-09-11
- Last Posted Date
- 2007-04-09
- Lead Sponsor
- Boston University
- Target Recruit Count
- 33
- Registration Number
- NCT00374478
- Locations
- 🇸🇪
Kalmar Maritime Academy, Kalmar, Sweden
The Antidepressant Efficacy of the Anticholinergic Scopolamine
- First Posted Date
- 2006-08-30
- Last Posted Date
- 2016-11-10
- Lead Sponsor
- National Institute of Mental Health (NIMH)
- Target Recruit Count
- 17
- Registration Number
- NCT00369915
- Locations
- 🇺🇸
National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States
Drug Development Updates
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