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Podophyllotoxin

Generic Name
Podophyllotoxin
Brand Names
Condylox
Drug Type
Small Molecule
Chemical Formula
C22H22O8
CAS Number
518-28-5
Unique Ingredient Identifier
L36H50F353

Overview

A lignan found in podophyllin resin from the roots of podophyllum plants. It is a potent spindle poison, toxic if taken internally, and has been used as a cathartic. It is very irritating to skin and mucous membranes, has keratolytic actions, has been used to treat warts and keratoses, and may have antineoplastic properties, as do some of its congeners and derivatives.

Background

A lignan found in podophyllin resin from the roots of podophyllum plants. It is a potent spindle poison, toxic if taken internally, and has been used as a cathartic. It is very irritating to skin and mucous membranes, has keratolytic actions, has been used to treat warts and keratoses, and may have antineoplastic properties, as do some of its congeners and derivatives.

Indication

For treatment of external genital warts (Condyloma acuminatum).

Associated Conditions

  • External Genital Warts
  • Perianal Warts

FDA Approved Products

Podofilox
Manufacturer:Actavis Pharma, Inc.
Route:TOPICAL
Strength:5 mg in 1 mL
Approved: 2023/07/17
NDC:0591-3204
Podofilox
Manufacturer:Padagis US LLC
Route:TOPICAL
Strength:5 mg in 1 g
Approved: 2023/05/01
NDC:0574-0621
Condylox
Manufacturer:Allergan, Inc.
Route:TOPICAL
Strength:5 mg in 1 g
Approved: 2024/02/08
NDC:0023-6118
PODOFILOX
Manufacturer:Padagis US LLC
Route:TOPICAL
Strength:5 mg in 1 mL
Approved: 2018/11/12
NDC:0574-0611
Podofilox
Manufacturer:Bryant Ranch Prepack
Route:TOPICAL
Strength:5 mg in 1 mL
Approved: 2022/01/20
NDC:63629-8832

Singapore Approved Products

No Singapore products found for this drug

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