The innovative Octopus trial represents the world's first multi-armed, multi-staged clinical study specifically designed to test multiple potential treatments for progressive multiple sclerosis simultaneously.
A network meta-analysis reveals that pregabalin and topiramate, with or without vitamin D3, significantly reduce migraine frequency in children and adolescents.
The OCTOPUS trial, a multi-arm study, is assessing R/S alpha-lipoic acid and metformin for progressive multiple sclerosis, aiming to enroll 375 participants in its first stage.
A series of case studies highlights the potential benefits of extended-course nirmatrelvir/ritonavir treatment for individuals suffering from Long COVID, with some patients reporting significant improvements in symptoms. The treatment, typically used for acute COVID-19 infections, was administered outside of the acute phase, offering new insights into managing Long COVID.
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