Overview

Zytron (DMPA) is under investigation for the treatment and health services research of HIV, Lactation, Contraception, Postpartum Depression, and Immune Cells (Mucosal and Systemic). DMPA has been investigated for the prevention, treatment, and basic science of Weight and Microbiota.

Indication

No indication information available.

Associated Conditions

No associated conditions information available.

Research Report

Published: Sep 29, 2025

A Comprehensive Analysis of Zytron: Disambiguation and Profiling of a Herbicide (DMPA, CAS 299-85-4) and a Pharmaceutical (Ondansetron)

Executive Summary and Disambiguation of "Zytron"

Identification of a Critical Ambiguity

An investigation into the substance designated "Zytron," based on the provided identifiers—specifically CAS Number 299-85-4 and DrugBank ID DB11768—reveals a significant nomenclatural conflict. These identifiers are associated with two distinct and unrelated chemical entities, one an agrochemical and the other a pharmaceutical. The primary objective of this report is to systematically disambiguate these two substances, providing a definitive and comprehensive profile for each to resolve the existing confusion and prevent potential errors in scientific, regulatory, and clinical contexts.

The core of this ambiguity lies in the polysemous use of the trade name "Zytron." In such cases of conflicting information, the Chemical Abstracts Service (CAS) Registry Number serves as the most stable and universally accepted unique identifier for a chemical substance. Therefore, this analysis is anchored to the entity definitively identified by the provided CAS number. The broader implications of this ambiguity extend to the integrity of scientific databases and the systemic risks posed by overlapping commercial branding in disparate industries. The potential for data cross-contamination between agrochemical and pharmaceutical domains highlights a critical need for rigorous adherence to standardized, unique identifiers.

Introduction to Zytron (DMPA): The Herbicide

Continue reading the full research report

Clinical Trials

Title	Posted	Study ID	Phase	Status	Sponsor
Endometrial Biopsy in Progestin Contraceptive Users	2023/03/08	NCT05760144	Early Phase 1	Recruiting	Oregon Health and Science University
Impact of Contraceptives on Cervico-Vaginal Mucosa	2021/03/24	NCT04814927	Phase 4	Completed	Eastern Virginia Medical School
The Kampala Women's Bone Study	2018/03/14	NCT03464266	Phase 4	Completed	University of Washington
Clinical Study of Depo Provera Comparing Lay Health Workers and Clinically-trained Health Workers	2017/08/21	NCT03255941	Early Phase 1	Completed	FHI 360
Pharmacokinetics and Pharmacodynamics of DMPA With HIV PrEP	2017/06/23	NCT03197961	Early Phase 1	Completed	Sharon Achilles
The Evidence for Contraceptive Options and HIV Outcomes Trial	2015/09/15	NCT02550067	Not Applicable	Completed	FHI 360
Effectiveness of Levonorgestrel-intrauterine System (LNG-IUS) Versus Depot Medroxyprogesterone Acetate (DMPA) in Treatment of Pelvic Pain in Clinically Diagnosed Endometriotic Patients	2015/08/28	NCT02534688	Phase 4	Completed	King Chulalongkorn Memorial Hospital
Pharmacodynamics and Pharmacokinetics Study of Existing DMPA Contraceptive Methods	2015/05/28	NCT02456584	Phase 1	Completed	FHI 360
The Impact of Contraception on Postpartum Weight Loss	2014/05/21	NCT02144259	Not Applicable	Completed	University of Pennsylvania
HIV-Target Cell Response in Women Initiating Various Contraceptive Methods in High HIV-Incidence Areas: Zim CHIC	2014/01/16	NCT02038335	N/A	Completed	University of Pittsburgh

FDA Drug Approvals

Approved Product	Manufacturer	NDC Code	Route	Strength	Effective Date
No FDA approvals found for this drug.

EMA Drug Approvals

Approved Product	Authorization Holder	Status	Issued Date
No EMA approvals found for this drug.

HSA Drug Approvals

Approved Product	Manufacturer	Approval Number	Dosage Form	Strength	Approval Date
No HSA approvals found for this drug.

NMPA Drug Approvals

Approved Product	Company	Approval Number	Drug Type	Dosage Form	Approval Date
No NMPA approvals found for this drug.

PPB Drug Approvals

Approved Product	Registration No.	Company	Licence No.	Strength	Registration Date
No PPB approvals found for this drug.

TGA Drug Approvals

Approved Product	ARTG ID	Sponsor	Registration Type	Status	Registration Date
No TGA approvals found for this drug.

Health Canada Drug Approvals

Approved Product	Company	DIN	Dosage Form	Strength	Market Date
No Health Canada approvals found for this drug.

CIMA AEMPS Drug Approvals

Approved Product	Company	Registration Number	Pharmaceutical Form	Prescription Type	Status
No CIMA AEMPS (Spain) approvals found for this drug.

Philippines FDA Drug Approvals

Approved Product	Company	License Number	Dosage Form	Strength	Approval Date
No Philippines FDA approvals found for this drug.

Saudi SFDA Drug Approvals

Approved Product	Company	License Number	Dosage Form	Strength	Approval Date
No Saudi SFDA approvals found for this drug.

Malaysia NPRA Drug Approvals

Approved Product	Company	Registration Number	Dosage Form	Strength	Approval Date
No Malaysia NPRA approvals found for this drug.

UK EMC Drug Information

Medicine Name	MA Holder	MA Number	Pharmaceutical Form	Active Ingredient	Authorization Date
No UK EMC drug information found for this drug.

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