MedPath

Apple

Generic Name
Apple
Drug Type
Biotech
Unique Ingredient Identifier
B423VGH5S9
Background

Apple allergenic extract is used in allergenic testing.

Persist AI Raises $12M Series A, Launches Cloud Lab to Revolutionize Pharmaceutical Formulation Development

• Persist AI has secured $12 million in Series A funding to expand its AI-driven robotics platform that reduces drug formulation development time from years to months. • The company's Cloud Lab platform enables pharmaceutical companies to remotely develop formulations using robotic laboratory facilities, testing 700 formulations in two months compared to the industry standard of 10-15 per month. • Persist AI's technology miniaturizes testing processes, requiring just 1 mL of liquid and a few milligrams of material compared to traditional methods that need 1000 mL and several grams.

Roche and Regeneron Announce Multi-Billion Dollar Investments in US Manufacturing Amid Tariff Concerns

• Roche has committed $50 billion to expand its US operations over five years, including new manufacturing facilities and R&D centers, with plans to create over 12,000 new jobs nationwide. • Regeneron is investing more than $3 billion in US operations through a partnership with Fujifilm Diosynth Biotechnologies, nearly doubling its large-scale manufacturing capacity in the country. • These pharmaceutical investments come as President Trump continues to threaten sector-specific tariffs, with Roche stating it will eventually export more medicines from the US than it imports.

Northwestern Medicine Launches Landmark Study Using Apple Watch to Revolutionize AFib Treatment

• Northwestern Medicine researchers are initiating a seven-year clinical trial to determine if wearable technology can reduce continuous blood thinner use in atrial fibrillation patients, potentially decreasing bleeding risks and improving quality of life. • The REACT-AF trial will monitor participants using Apple Watch technology, implementing a "pill-in-pocket" approach where patients take anticoagulants only during detected AFib episodes rather than daily for life. • With AFib affecting over 5 million Americans and expected to reach 12.1 million by 2030, this NIH-funded study could fundamentally change treatment standards by personalizing anticoagulation therapy based on real-time heart rhythm monitoring.

EvolutionaryScale Launches with $142M to Transform Drug Discovery Using Advanced AI Protein Platform

• Former Meta researchers have launched EvolutionaryScale with $142 million in seed funding, backed by prominent tech investors and industry giants NVIDIA and Amazon. • The company's ESM3 platform, trained on 4 billion proteins, can generate novel protein structures that would naturally take millions of years to evolve, demonstrating breakthrough capabilities in protein engineering. • EvolutionaryScale plans to partner with pharmaceutical companies while offering free academic access through NVIDIA's BioNeMo platform, positioning itself as a major player in AI-driven drug discovery.
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