Amitriptyline
- Generic Name
- Amitriptyline
- Brand Names
- Elavil
- Drug Type
- Small Molecule
- Chemical Formula
- C20H23N
- CAS Number
- 50-48-6
- Unique Ingredient Identifier
- 1806D8D52K
- Background
Amitriptyline is a tricyclic antidepressant that has been used to treat depression for decades. ELAVIL, a previously approved branded product of amitriptyline, was first approved by the FDA in 1961. Amitriptyline has been investigated in the treatment of pain-related conditions, attributed to its analgesic properties.
- Indication
This drug in indicated for the following conditions :
Major depressive disorder in adults
Management of neuropathic pain in adults
Prophylactic treatment of chronic tension-type headache (CTTH) in adults
Prophylactic treatment of migraine in adults
...
- Associated Conditions
- Anorexia Nervosa (AN), Attention Deficit Hyperactivity Disorder (ADHD), Bulimia Nervosa, Depression, Depression Acute, Diabetic Neuropathies, Insomnia, Irritable Bowel Syndrome (IBS), Major Depressive Disorder (MDD), Migraine, Moderate Depression, Neuropathic Pain, Nocturnal Enuresis, Severe Depression, Sleep disorders and disturbances, Tension Headache, Moderate Agitation, Moderate Anxiety, Severe Anxiety, Severe agitation
- Associated Therapies
- -
Effects of Amitriptyline for the Treatment of Pain on Driving Performance and Cognition.
- Conditions
- First Posted Date
- 2005-09-16
- Last Posted Date
- 2005-09-16
- Lead Sponsor
- UMC Utrecht
- Target Recruit Count
- 24
- Registration Number
- NCT00189059
- Locations
- 🇳🇱
University of Utrecht, Utrecht, Netherlands
Efficacy of Amitriptyline for Painful Bladder Syndrome (PBS)
- Conditions
- Interventions
- First Posted Date
- 2005-07-27
- Last Posted Date
- 2013-10-30
- Target Recruit Count
- 271
- Registration Number
- NCT00124306
- Locations
- 🇺🇸
University of Washington, Seattle, Washington, United States
🇨🇦Queen's University, Kingston, Ontario, Canada
🇺🇸Stanford University Medical Center, Stanford, California, United States
Sham Device, Pill Placebo or Treatment For Arm Pain
- Conditions
- First Posted Date
- 2002-01-15
- Last Posted Date
- 2013-03-22
- Target Recruit Count
- 240
- Registration Number
- NCT00029497
- Locations
- 🇺🇸
Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States
🇺🇸Cambridge Hospital, Cambridge, Massachusetts, United States
Chronic Pain in Spinal Cord Injury
- Conditions
- First Posted Date
- 2000-11-02
- Last Posted Date
- 2012-12-18
- Target Recruit Count
- 100
- Registration Number
- NCT00006428
- Locations
- 🇺🇸
University of Washington, Department of Rehabilitation Medicine, Seattle, Washington, United States
Chronic Pain After Amputation
- Conditions
- First Posted Date
- 2000-11-02
- Last Posted Date
- 2016-09-26
- Target Recruit Count
- 125
- Registration Number
- NCT00006427
- Locations
- 🇺🇸
University of Washington, Department of Rehabilitation Medicine, Seattle, Washington, United States
Combining N-of-1 Trials to Assess Fibromyalgia Treatments
- Conditions
- Interventions
- First Posted Date
- 2000-01-19
- Last Posted Date
- 2013-08-01
- Lead Sponsor
- Tufts Medical Center
- Target Recruit Count
- 58
- Registration Number
- NCT00000428
- Locations
- 🇺🇸
Office of Raphael Kieval, MD, Brockton, Massachusetts, United States
🇺🇸Office of Eileen Winston, MD, Framingham, Massachusetts, United States
🇺🇸Newton-Wellesley Hospital, Newton, Massachusetts, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.