Niacin

Generic Name
Niacin
Brand Names
Advicor, Concept Ob, Irospan 24/6 Kit, Mvc-fluoride, Niacor, Niaspan, Niodan, Simcor, Vitafol-one
Drug Type
Small Molecule
Chemical Formula
C6H5NO2
CAS Number
59-67-6
Unique Ingredient Identifier
2679MF687A
Background

Niacin is a B vitamin used to treat vitamin deficiencies as well as hyperlipidemia, dyslipidemia, hypertriglyceridemia, and to reduce the risk of myocardial infarctions.

Indication

Niacin is indicated to prevent vitamin deficiencies in pediatric and adult patients receiving parenteral nutrition as part of multivitamin intravenous injections. Niacin oral tablets are indicated as a monotherapy or in combination with simvastatin or lovastatin to treat primary hyperlipidemia and mixed dyslipidemia. It can also be used to reduce the risk of...

Associated Conditions
Atherosclerosis, High Cholesterol, High Triglyceride Level, Mixed Dyslipidemias, Nonfatal Myocardial Infarction, Pellagra, Primary Hypercholesterolemia, Severe Hypertriglyceridemia (sHTG), Type II Hyperlipidaemia
Associated Therapies
Dietary supplementation
Clinical Trials
Related News

A Prospective, Open Label Comparison of Ezetimibe, Niacin, and Colestipol as Adjunct Therapy in Lipid Reduction

First Posted Date
2005-09-20
Last Posted Date
2014-08-12
Lead Sponsor
Tuscaloosa Research & Education Advancement Corporation
Target Recruit Count
30
Registration Number
NCT00203476
Locations
🇺🇸

Tuscaloosa Research & Education Advancement Corporation, Tuscaloosa, Alabama, United States

Nicotinic Acid - Pharmacokinetics, Pharmacodynamics, Receptor Expression

Phase 1
Conditions
Healthy
First Posted Date
2005-09-15
Last Posted Date
2006-03-15
Lead Sponsor
Heidelberg University
Target Recruit Count
18
Registration Number
NCT00176020

High-Density Lipoprotein (HDL) Cholesterol Increased Plaque Stabilization in the Elderly

First Posted Date
2005-08-05
Last Posted Date
2017-11-06
Lead Sponsor
Johns Hopkins University
Target Recruit Count
145
Registration Number
NCT00127218
Locations
🇺🇸

Johns Hopkins Unversity School of Medicine, Baltimore, Maryland, United States

Comparative Efficacy Evaluation of Lipids When Treated With Niaspan & Statin or Other Lipid-Modifying Therapies-COMPELL

First Posted Date
2004-03-12
Last Posted Date
2006-11-01
Lead Sponsor
Kos Pharmaceuticals
Target Recruit Count
300
Registration Number
NCT00079638

Niacin for Treatment of Elevated Cholesterol and Triglycerides in HIV-Infected Patients

First Posted Date
2002-09-25
Last Posted Date
2011-03-02
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
30
Registration Number
NCT00046267
Locations
🇺🇸

Washington Univ (St. Louis), St. Louis, Missouri, United States

🇺🇸

Stanford Univ, Stanford, California, United States

🇺🇸

Case Western Reserve Univ, Cleveland, Ohio, United States

and more 13 locations

Cholesterol-Lowering Atherosclerosis Study (CLAS)

First Posted Date
1999-10-28
Last Posted Date
2013-12-13
Lead Sponsor
National Heart, Lung, and Blood Institute (NHLBI)
Registration Number
NCT00000599

Coronary Drug Project

First Posted Date
1999-10-28
Last Posted Date
2013-11-26
Lead Sponsor
National Heart, Lung, and Blood Institute (NHLBI)
Registration Number
NCT00000482

Coronary Drug Project Mortality Surveillance

First Posted Date
1999-10-28
Last Posted Date
2013-11-26
Lead Sponsor
National Heart, Lung, and Blood Institute (NHLBI)
Registration Number
NCT00000483

HDL-Atherosclerosis Treatment Study (HATS)

First Posted Date
1999-10-28
Last Posted Date
2016-02-10
Lead Sponsor
University of Washington
Registration Number
NCT00000553

Familial Atherosclerosis Treatment Study

First Posted Date
1999-10-28
Last Posted Date
2015-12-03
Lead Sponsor
University of Washington
Target Recruit Count
146
Registration Number
NCT00000512
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