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Niacin

Generic Name
Niacin
Brand Names
Advicor, Concept Ob, Irospan 24/6 Kit, Mvc-fluoride, Niacor, Niaspan, Niodan, Simcor, Vitafol-one
Drug Type
Small Molecule
Chemical Formula
C6H5NO2
CAS Number
59-67-6
Unique Ingredient Identifier
2679MF687A

Overview

Niacin is a B vitamin used to treat vitamin deficiencies as well as hyperlipidemia, dyslipidemia, hypertriglyceridemia, and to reduce the risk of myocardial infarctions.

Background

Niacin is a B vitamin used to treat vitamin deficiencies as well as hyperlipidemia, dyslipidemia, hypertriglyceridemia, and to reduce the risk of myocardial infarctions.

Indication

Niacin is indicated to prevent vitamin deficiencies in pediatric and adult patients receiving parenteral nutrition as part of multivitamin intravenous injections. Niacin oral tablets are indicated as a monotherapy or in combination with simvastatin or lovastatin to treat primary hyperlipidemia and mixed dyslipidemia. It can also be used to reduce the risk of nonfatal myocardial infarctions in patients with a history of myocardial infarction and hyperlipidemia. Niacin is also indicated with bile acid binding resins to treat atherosclerosis in patients with coronary artery disease and hyperlipidemia or to treat primary hyperlipidemia. Finally niacin is indicated to treat severe hypertriglyceridemia.

Associated Conditions

  • Atherosclerosis
  • High Cholesterol
  • High Triglyceride Level
  • Mixed Dyslipidemias
  • Nonfatal Myocardial Infarction
  • Pellagra
  • Primary Hypercholesterolemia
  • Severe Hypertriglyceridemia (sHTG)
  • Type II Hyperlipidaemia

Clinical Trials

Early Phase 1
Withdrawn
Posted: 2014/04/10
Sponsor:
George Thanassoulis
Phase 2
Completed
Posted: 2013/12/24
Sponsor:
McGill University He...
Phase 4
Completed
Posted: 2013/09/13
Sponsor:
University of Campin...

FDA Approved Products

Multivitamin with fluoride
Manufacturer:A-S Medication Solutions
Route:ORAL
Strength:13.5 mg in 1 1
Approved: 2017/06/01
NDC:50090-0435
Multi-Vitamin Fluoride Drops
Manufacturer:H.J. Harkins Company, Inc.
Route:ORAL
Strength:8 mg in 1 mL
Approved: 2011/10/25
NDC:52959-593
NIACIN
Manufacturer:Chartwell RX, LLC
Route:ORAL
Strength:1000 mg in 1 1
Approved: 2023/03/10
NDC:62135-498
Niaspan
Manufacturer:Dispensing Solutions, Inc.
Route:ORAL
Strength:500 mg in 1 1
Approved: 2011/10/18
NDC:68258-6032
Niacin
Manufacturer:Aurobindo Pharma Limited
Route:ORAL
Strength:750 mg in 1 1
Approved: 2023/02/15
NDC:59651-019

Singapore Approved Products

No Singapore products found for this drug

Drug Development Updates

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