Amodiaquine
生产企业：Parke davis div warner lambert co
Amodiaquine is an antimalarial drug.
Amodiaquine is an antimalarial drug.
The mechanism of plasmodicidal action of amodiaquine is not completely certain. Like other quinoline derivatives, it is thought to inhibit heme polymerase activity. This results in accumulation of free heme, which is toxic to the parasites. The drug binds the free heme preventing the parasite from converting it to a form less toxic. This drug-heme complex is toxic and disrupts membrane function.
For treatment of acute malarial attacks in non-immune subjects.
每项发明一条，涵盖美国、欧洲、PCT 与中国的同族专利。
