MedPath

Amodiaquine

Generic Name
Amodiaquine
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C20H22ClN3O
CAS Number
86-42-0
Unique Ingredient Identifier
220236ED28
Background

A 4-aminoquinoquinoline compound with anti-inflammatory properties.

Indication

For treatment of acute malarial attacks in non-immune subjects.

Associated Conditions
-
Associated Therapies
-

Relationship Between HIV and Malaria in Ugandan Children

Completed
Conditions
HIV Infections
Malaria
Interventions
First Posted Date
2006-07-26
Last Posted Date
2021-11-01
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
300
Registration Number
NCT00356824
Locations
🇺🇬

Pediatric Infectious Diseases Clinic, Mulago Hospital Complex, Kampala, Uganda

Safety and Efficacy of Methylene Blue Combined With Artesunate or Amodiaquine for Malaria Treatment in Children of Burkina Faso: a Pilot Study

Phase 2
Completed
Conditions
Malaria
First Posted Date
2006-07-20
Last Posted Date
2006-10-24
Lead Sponsor
Heidelberg University
Registration Number
NCT00354380
Locations
🇧🇫

Nouna District Hospital, Nouna, Burkina Faso

Long-Term Follow-up of Children for a 2-Year Period to Confirm the Safety and Immunogenicity of GSK 257049 Vaccine

Phase 2
Completed
Conditions
Malaria
Interventions
Biological: GSK Biologicals' candidate Plasmodium falciparum malaria vaccine 257049
Biological: Hiberix®
Biological: Engerix™-B
Biological: Prevnar™
Drug: sulfadoxine-pyrimethamine
Drug: amodiaquine
First Posted Date
2006-05-09
Last Posted Date
2016-12-09
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
1737
Registration Number
NCT00323622
Locations
🇲🇿

GSK Investigational Site, Maputo, Mozambique

Efficacy of Amodiaquine in the Treatment of Uncomplicated Falciparum Malaria in Young Children of Burkina Faso

Phase 2
Completed
Conditions
Malaria
First Posted Date
2005-12-02
Last Posted Date
2010-02-03
Lead Sponsor
Heidelberg University
Target Recruit Count
120
Registration Number
NCT00261222
Locations
🇧🇫

Centre de Recherche en Santé de Nouna (CRSN), Nouna, Burkina Faso

Chloroquine and Amodiaquine for Treatment of Malaria in Children

Phase 4
Completed
Conditions
Malaria, Falciparum
First Posted Date
2005-08-30
Last Posted Date
2008-04-08
Lead Sponsor
Bandim Health Project
Target Recruit Count
720
Registration Number
NCT00137514
Locations
🇬🇼

Bandim Health Project, Apartado 861, Bissau, Guinea-Bissau

A Trial of Four Drug Regimens for the Prevention of Malaria in Senegalese Children

Phase 3
Completed
Conditions
Malaria
First Posted Date
2005-08-22
Last Posted Date
2017-01-12
Lead Sponsor
London School of Hygiene and Tropical Medicine
Target Recruit Count
2200
Registration Number
NCT00132548
Locations
🇸🇳

Institut de recherche pour le developpement, Dakar, Senegal

Efficacy and Safety of Sulphadoxine-pyrimethamine and Amodiaquine in Ghanaian Pregnant Women

Phase 3
Completed
Conditions
Malaria
Pregnancy
First Posted Date
2005-08-19
Last Posted Date
2017-01-12
Lead Sponsor
London School of Hygiene and Tropical Medicine
Target Recruit Count
900
Registration Number
NCT00131703

Antimalarial Drug Resistance in Mali

Not Applicable
Completed
Conditions
Malaria
First Posted Date
2005-08-09
Last Posted Date
2006-08-16
Lead Sponsor
Centers for Disease Control and Prevention
Target Recruit Count
1011
Registration Number
NCT00127998
Locations
🇲🇱

Koro Health Center, Koro, Mali

🇲🇱

Faladje Missionary Dispensary, Faladje, Mali

🇲🇱

Pongono Community Health Center, Pongono, Mali

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