Ivabradine
- Generic Name
- Ivabradine
- Brand Names
- Corlanor, Lancora, Procoralan, Corlentor, Ivabradine Accord, Ivabradine Anpharm, Ivabradine Zentiva
- Drug Type
- Small Molecule
- Chemical Formula
- C27H36N2O5
- CAS Number
- 155974-00-8
- Unique Ingredient Identifier
- 3H48L0LPZQ
- Background
Ivabradine is a novel heart rate lowering medicine for the symptomatic management of stable angina pectoralis and symptomatic chronic heart failure. Ivabradine, brand name Corlanor, was approved by the FDA in April 2015 for the treatment of chronic heart failure in patients with an ejection fraction of ≤35%, in sinus rhythm with resting heart rate ≥70 beats ...
- Indication
Ivabradine is indicated by the FDA to reduce the risk of hospitalization for worsening heart failure in adult patients with stable, symptomatic chronic heart failure with left ventricular ejection fraction ≤35%, who are in sinus rhythm with resting heart rate ≥70 beats per minute and either are on maximally tolerated doses of beta-blockers or have a contrain...
- Associated Conditions
- Chronic Heart Failure (CHF), Chronic Stable Angina Pectoris, Left Ventricular Dysfunction, Chronic, stable, symptomatic Heart Failure
- Associated Therapies
- -
Comparison Between Atenolol,Propnalol and Ivabradine
- Conditions
- Interventions
- First Posted Date
- 2024-11-01
- Last Posted Date
- 2024-11-01
- Lead Sponsor
- Menoufia University
- Target Recruit Count
- 120
- Registration Number
- NCT06670690
- Locations
- 🇪🇬
Menoufia University, Shepien El Kom, Menoufia Government, Egypt
Role of Ivabradine on Heart Rate and Quality of Life in Patients With Mitral Stenosis in Sinus Rhythm
- First Posted Date
- 2024-04-17
- Last Posted Date
- 2024-04-17
- Target Recruit Count
- 42
- Registration Number
- NCT06371222
- Locations
- 🇧🇩
BSMMU, Dhaka, Bangladesh
Value of Heart Rate Lowering Therapy in Acute Myocarditis
- First Posted Date
- 2024-03-15
- Last Posted Date
- 2024-03-15
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 150
- Registration Number
- NCT06312891
- Locations
- 🇪🇬
Heart Hospital, Assiut, Egypt
RECOVER-AUTONOMIC: Platform Protocol, Appendix B (Ivabradine)
- Conditions
- Interventions
- First Posted Date
- 2024-03-12
- Last Posted Date
- 2024-06-27
- Lead Sponsor
- Kanecia Obie Zimmerman
- Target Recruit Count
- 180
- Registration Number
- NCT06305806
- Locations
- 🇺🇸
All sites listed under NCT06305780, Durham, North Carolina, United States
Effect of Heart Rate Control With Ivabradine on Hemodynamic in Patients With Sepsis
- Conditions
- Interventions
- First Posted Date
- 2023-05-31
- Last Posted Date
- 2024-01-29
- Target Recruit Count
- 172
- Registration Number
- NCT05882708
- Locations
- 🇨🇳
the Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China
Ivabradine for Long-Term Effects of COVID-19 With POTS Cohort
- Conditions
- Interventions
- First Posted Date
- 2022-08-01
- Last Posted Date
- 2023-11-29
- Target Recruit Count
- 250
- Registration Number
- NCT05481177
- Locations
- 🇺🇸
Uniformed Services University, Bethesda, Maryland, United States
Clinical Study of CMR to Evaluate the Effect of Ivabradine on the Improvement of Left Ventricular Remodeling in STEMI Patients After Primary PCI
- First Posted Date
- 2022-04-27
- Last Posted Date
- 2022-04-27
- Lead Sponsor
- Qian geng
- Target Recruit Count
- 240
- Registration Number
- NCT05348057
- Locations
- 🇨🇳
Chinese People's Liberation Army General Hospital, Peking, Beijing, China
Ivabradine for Prevention of Myocardial Injury After Noncardiac Surgery Trial (PREVENT-MINS)
- Conditions
- Interventions
- First Posted Date
- 2022-03-15
- Last Posted Date
- 2024-08-14
- Lead Sponsor
- Jagiellonian University
- Target Recruit Count
- 2500
- Registration Number
- NCT05279651
- Locations
- 🇵🇱
Szpital Uniwersytecki nr 1 im. dr Antoniego Jurasza w Bydgoszczy, Bydgoszcz, Poland
🇵🇱Specjalistyczny Szpital Wojewódzki w Ciechanowie, Ciechanów, Poland
🇵🇱ZZOZ Szpital Śląski w Cieszynie, Cieszyn, Poland
Heart Rate Controller in Computed Tomography Coronary Angiography
- Conditions
- Interventions
- First Posted Date
- 2022-03-02
- Last Posted Date
- 2022-05-17
- Lead Sponsor
- Mahidol University
- Target Recruit Count
- 246
- Registration Number
- NCT05261464
- Locations
- 🇹🇭
Department of Internal Medicine, Faculty of Medicine, Siriraj Hospital Mahidol University, Bangkok, Bangkoknoi, Thailand
the Role of Ivabradine in Causing AF in Patients With Chronic Coronary Syndrome
- First Posted Date
- 2021-12-23
- Last Posted Date
- 2021-12-28
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 180
- Registration Number
- NCT05168189
Drug Development Updates
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