Tamsulosin
- Generic Name
- Tamsulosin
- Brand Names
- Flomax, Jalyn
- Drug Type
- Small Molecule
- Chemical Formula
- C20H28N2O5S
- CAS Number
- 106133-20-4
- Unique Ingredient Identifier
- G3P28OML5I
- Background
Tamsulosin is a selective alpha-1A and alpha-1B adrenoceptor antagonist that exerts its greatest effect in the prostate and bladder, where these receptors are most common. It is indicated for the treatment of signs and symptoms of benign prostatic hypertrophy. Antagonism of these receptors leads to relaxation of smooth muscle in the prostate and detrusor mus...
- Indication
Tamsulosin is indicated for the treatment of signs and symptoms of benign prostatic hyperplasia.
Tamsulosin is also used off label for the treatment of ureteral stones, prostatitis, and female voiding dysfunction.
- Associated Conditions
- Benign Prostatic Hyperplasia (BPH), Benign Prostatic Hypertrophy, Bladder Outlet Obstruction, Ureteral Calculus
- Associated Therapies
- -
PARTIQoL Trial: Proton Therapy vs IMRT for Localized Prostate Cancer
Jason Efstathiou discusses the PARTIQoL trial, comparing proton beam therapy to IMRT for localized prostate cancer, focusing on patient-reported outcomes and bowel function at 24 months. The trial, involving 450 patients from 29 centers, employs innovative strategies to overcome accrual challenges, emphasizing rigorous data generation to assess proton therapy's benefits. Despite proton therapy's potential advantages, its limited availability and high costs in the U.S. highlight the need for comparative studies like PARTIQoL.
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