Tamsulosin

Generic Name
Tamsulosin
Brand Names
Flomax, Jalyn
Drug Type
Small Molecule
Chemical Formula
C20H28N2O5S
CAS Number
106133-20-4
Unique Ingredient Identifier
G3P28OML5I
Background

Tamsulosin is a selective alpha-1A and alpha-1B adrenoceptor antagonist that exerts its greatest effect in the prostate and bladder, where these receptors are most common. It is indicated for the treatment of signs and symptoms of benign prostatic hypertrophy. Antagonism of these receptors leads to relaxation of smooth muscle in the prostate and detrusor mus...

Indication

Tamsulosin is indicated for the treatment of signs and symptoms of benign prostatic hyperplasia.

Tamsulosin is also used off label for the treatment of ureteral stones, prostatitis, and female voiding dysfunction.

Associated Conditions
Benign Prostatic Hyperplasia (BPH), Benign Prostatic Hypertrophy, Bladder Outlet Obstruction, Ureteral Calculus
Associated Therapies
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Comparison of Medical and Surgical Treatments of Benign Prostate Hyperplasia in Patients Who Have Low Grade Non Muscle Invasive Bladder Cancer for Tumour Recurrence and Progression

First Posted Date
2015-05-14
Last Posted Date
2015-05-14
Lead Sponsor
Diskapi Teaching and Research Hospital
Target Recruit Count
40
Registration Number
NCT02443844
Locations
🇹🇷

Turkish Ministry of Health Dıskapı Yıldırım Beyazıt Training and Research Hospital, Ankara, Turkey

Silodosin Versus Tamsulosin for Treatment of Ureteral Stones

First Posted Date
2015-02-24
Last Posted Date
2020-06-23
Lead Sponsor
Albert Einstein Healthcare Network
Target Recruit Count
1
Registration Number
NCT02369744
Locations
🇺🇸

Einstein Medical Center Philadelphia, Philadelphia, Pennsylvania, United States

Efficacy And Safety Of Combination Therapy For Treatment Of Overactive Bladder In Male Patients With Benign Prostatic Hyperplasia.

First Posted Date
2014-10-31
Last Posted Date
2021-03-19
Lead Sponsor
St. Joseph's Healthcare Hamilton
Target Recruit Count
200
Registration Number
NCT02279615
Locations
🇨🇦

St. Joseph's Healthcare Hamilton - McMaster Institute of Urology, Hamilton, Ontario, Canada

Study to Investigate the Effect of Paroxetine Mediated CYP2D6 Inhibition on the Pharmacokinetics of Tamsulosin in Healthy Male Volunteers

Phase 1
Completed
Conditions
Interventions
First Posted Date
2014-10-15
Last Posted Date
2014-10-15
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
24
Registration Number
NCT02264184

Safety Profile of Secotex ® in Patients With Benign Prostatic Hyperplasia

Completed
Conditions
Interventions
First Posted Date
2014-09-19
Last Posted Date
2014-09-19
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
982
Registration Number
NCT02245529

Study to Evaluate the Symptomatic Relief Effects of FLOMAX® in Patients With Signs and Symptoms of Benign Prostatic Hyperplasia

Phase 4
Completed
Conditions
Interventions
First Posted Date
2014-09-19
Last Posted Date
2014-09-19
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
493
Registration Number
NCT02244242

Observational Study of ALNA® (Tamsulosin) in Patients With Benign Prostatic Hyperplasia (BPH)

Completed
Conditions
Interventions
First Posted Date
2014-09-19
Last Posted Date
2014-09-19
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
7391
Registration Number
NCT02245503

Observational Study in Patients With Functional Benign Prostatic Hyperplasia Symptoms Who Switched From Phytotherapy to ALNA® (Tamsulosin)

Completed
Conditions
Interventions
First Posted Date
2014-09-19
Last Posted Date
2014-09-19
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
4150
Registration Number
NCT02244320

Study of FLOMAX® Versus Placebo in Female Patients With Lower Urinary Tract Symptoms (LUTS) With a Significant Component of Voiding Symptoms

First Posted Date
2014-09-19
Last Posted Date
2014-09-19
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
74
Registration Number
NCT02244281
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