羟基喜树碱

10-hydroxycamptothecin

未知生产厂商

10-hydroxycamptothecin is under investigation in clinical trial NCT00956787 (Study of AR-67 (DB-67) in Myelodysplastic Syndrome (MDS)).

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概览

10-hydroxycamptothecin is under investigation in clinical trial NCT00956787 (Study of AR-67 (DB-67) in Myelodysplastic Syndrome (MDS)).

技术标识符

化学式: C₂₀H₁₆N₂O₅
CAS 编号: 19685-09-7
UNII ID: 9Z01632KRV

专利

每项发明一条，涵盖美国、欧洲、PCT 与中国的同族专利。

Multi-arm polymeric conjugates of 7-ethyl-10-hydroxycamptothecin for treatment of breast, colorectal, pancreatic, ovarian and lung cancers
- US 7462627 B2
  申请人: ENZON PHARMACEUTICALS INC优先权: 2006
  CN
  EP
  US
  WO
  9 件公开
- EP 1996208 B1
  申请人: BELROSE PHARMA INC优先权: 2006
  CN
  EP
  WO
  3 件公开
Treatment of resistant or refractory cancers with multi-arm polymeric conjugates of 7-ethyl-10-hydroxycamptothecin
EP 2109448 B1申请人: ENZON PHARMACEUTICALS INC优先权: 2007
CN
EP
US
WO
6 件公开
7-ETHYL-10-HYDROXYCAMPTOTHECIN DRUG PRECURSOR WITH FLUORESCENCE ACTIVITY, AND PREPARATION METHOD AND USE THEREOF
US 2024156990 A1申请人: UNIV SOOCHOW优先权: 2021
CN
US
WO
4 件公开
Method of manufacturing of 7-ethyl-10-hydroxycamptothecin
US 7544801 B2申请人: PLIVA LACHEMA AS优先权: 2003
US
4 件公开
Crystalline polymorph of 7-ethyl-10-hydroxycamptothecin
US 2009012111 A1申请人: SCINOPHARM TAIWAN LTD优先权: 2008
CN
US
3 件公开
Pharmaceutical Formulation for Increasing Solubility of 10-Hydroxycamptothecin Compounds in Non-Aqueous Polar Solvents
US 2007254905 A1申请人: SAMYANG CORP优先权: 2004
CN
US
2 件公开
TREATMENT OF NEUROBLASTOMA WITH MULTI-ARM POLYMERIC CONJUGATES OF 7-ETHYL-10-HYDROXYCAMPTOTHECIN
US 2010098654 A1申请人: PASTORINO FABIO优先权: 2009
CN
US
2 件公开
METHODS FOR INHIBITING ANGIOGENESIS WITH MULTI-ARM POLYMERIC CONJUGATES OF 7-ETHYL-10-HYDROXYCAMPTOTHECIN
US 2012122956 A1申请人: PASTORINO FABIO优先权: 2010
CN
US
2 件公开
METHODS OF TREATING HER2 POSITIVE CANCER WITH HER2 RECEPTOR ANTAGONIST IN COMBINATION WITH MULTI-ARM POLYMERIC CONJUGATES OF 7-ETHYL-10-HYDROXYCAMPTOTHECIN
US 2012171201 A1申请人: SAPRA PUJA优先权: 2010
CN
US
2 件公开
7-ETHYL-10-HYDROXYCAMPTOTHECIN DERIVATIVES FOR USE IN THE TREATMENT OF CANCER
EP 3971189 A1申请人: NARODOWY INST LEKOW优先权: 2020
EP
US
2 件公开

药物

羟基喜树碱

概览

专利

Multi-arm polymeric conjugates of 7-ethyl-10-hydroxycamptothecin for treatment of breast, colorectal, pancreatic, ovarian and lung cancers