MedPath

Icodextrin

Generic Name
Icodextrin
Brand Names
Extraneal
Drug Type
Small Molecule
CAS Number
337376-15-5
Unique Ingredient Identifier
2NX48Z0A9G

Overview

Icodextrin is an iso-osmotic peritoneal dialysis solution containing glucose polymers. It is used primarily for ambulatory peritoneal dialysis (CAPD) of diabetic patients and automated peritoneal dialysis (APD) for patients with end-stage renal disease. It is injected as a solution into the peritoneal cavity. The drug is absorbed via convective transport via peritoneal lymphatic pathways.

Background

Icodextrin is an iso-osmotic peritoneal dialysis solution containing glucose polymers. It is used primarily for ambulatory peritoneal dialysis (CAPD) of diabetic patients and automated peritoneal dialysis (APD) for patients with end-stage renal disease. It is injected as a solution into the peritoneal cavity. The drug is absorbed via convective transport via peritoneal lymphatic pathways.

Indication

Used for continuous ambulatory peritoneal dialysis (CAPD) of diabetic patients or automated peritoneal dialysis (APD) for the management of end-stage renal disease.

Associated Conditions

No associated conditions information available.

FDA Approved Products

EXTRANEAL
Manufacturer:Vantive US Healthcare LLC
Route:INTRAPERITONEAL
Strength:7.5 g in 100 mL
Approved: 2025/05/07
NDC:0941-0719
EXTRANEAL
Manufacturer:Vantive US Healthcare LLC
Route:INTRAPERITONEAL
Strength:7.5 g in 100 mL
Approved: 2025/05/07
NDC:0941-0681
EXTRANEAL
Manufacturer:Baxter Healthcare Corporation
Route:INTRAPERITONEAL
Strength:7.5 g in 100 mL
Approved: 2020/09/24
NDC:0941-0679
EXTRANEAL
Manufacturer:Vantive US Healthcare LLC
Route:INTRAPERITONEAL
Strength:7.5 g in 100 mL
Approved: 2025/05/07
NDC:0941-0717
EXTRANEAL
Manufacturer:Vantive US Healthcare LLC
Route:INTRAPERITONEAL
Strength:7.5 g in 100 mL
Approved: 2025/05/07
NDC:0941-0681

Singapore Approved Products

EXTRANEAL PERITONEAL DIALYSIS SOLUTION 75 g/l
Manufacturer:BAXTER HEALTHCARE SA, SINGAPORE BRANCH, BAXTER HEALTHCARE SA
Form:SOLUTION, STERILE
Strength:75 g/l
Online:Yes
Approved: 1999/11/09
Approval:SIN11220P

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