Domperidone
- Generic Name
- Domperidone
- Brand Names
- -
- Drug Type
- Small Molecule
- Chemical Formula
- C22H24ClN5O2
- CAS Number
- 57808-66-9
- Unique Ingredient Identifier
- 5587267Z69
- Background
A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
- Indication
For management of dyspepsia, heartburn, epigastric pain, nausea, and vomiting.
- Associated Conditions
- Diabetic Gastroparesis, Dyspepsia, Erosive Esophagitis, Gastrointestinal Symptoms, Non-erosive Reflux Esophagitis Disease (NERD), Upper gastrointestinal motility disorders
- Associated Therapies
- -
Study of Effects of Preoperative Oral Domperidone on Gastric Residual Volume After Clear Fluid Ingestion in Patients Scheduled for Elective Surgeries
- First Posted Date
- 2022-10-06
- Last Posted Date
- 2023-05-15
- Lead Sponsor
- Ain Shams University
- Target Recruit Count
- 40
- Registration Number
- NCT05570292
- Locations
- 🇪🇬
Ain Shams University hospitals, Cairo, Egypt
Compassionate Use of Domperidone for Refractory Gastroparesis
- Conditions
- Interventions
- First Posted Date
- 2021-01-07
- Last Posted Date
- 2023-07-17
- Lead Sponsor
- Children's Mercy Hospital Kansas City
- Target Recruit Count
- 20
- Registration Number
- NCT04699591
- Locations
- 🇺🇸
Children's Mercy Hospitals and Clinics, Kansas City, Missouri, United States
The Effect of Antiemetics on Bowel Preparation Before Colonoscopy
- First Posted Date
- 2020-10-12
- Last Posted Date
- 2020-10-12
- Lead Sponsor
- RenJi Hospital
- Target Recruit Count
- 200
- Registration Number
- NCT04583111
- Locations
- 🇨🇳
Shengliang Chen, Shanghai, China
Effectiveness of Prokinetic Agents in Improving Abdominal Discomfort at Colonoscopy
- First Posted Date
- 2019-09-26
- Last Posted Date
- 2021-09-02
- Lead Sponsor
- Mahidol University
- Target Recruit Count
- 525
- Registration Number
- NCT04104867
- Locations
- 🇹🇭
Chairat Supsamutchai, Bangkok, Bankok, Thailand
Domperidone and Risk of Serious Cardiac Events in Postpartum Women
- Conditions
- Interventions
- First Posted Date
- 2019-07-18
- Last Posted Date
- 2021-07-07
- Target Recruit Count
- 184929
- Registration Number
- NCT04024865
- Locations
- 🇨🇦
Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Quebec, Canada
The Use Of Domperidone For The Relief Of Refractory Upper Gastrointestinal GI Symptoms
- Conditions
- First Posted Date
- 2019-01-18
- Last Posted Date
- 2024-02-08
- Lead Sponsor
- Jill Deutsch
- Registration Number
- NCT03810287
- Locations
- 🇺🇸
Yale Digestive Diseases, New Haven, Connecticut, United States
EFFECT OF LOW LEVEL LASER THERAPY VERSUS ELECTROACUPUNCTURE ON POSTNATAL SCANTY MILK SECRETION
- Conditions
- Interventions
- First Posted Date
- 2019-01-16
- Last Posted Date
- 2019-01-16
- Lead Sponsor
- Cairo University
- Target Recruit Count
- 60
- Registration Number
- NCT03806062
- Locations
- 🇪🇬
Kasr Alainy medical school, Cairo, Egypt
Effect of Domperidone on Completion Rate of Vedio Capsule Endoscopy
- Conditions
- Interventions
- First Posted Date
- 2018-09-07
- Last Posted Date
- 2018-12-17
- Lead Sponsor
- Children's Hospital of Fudan University
- Target Recruit Count
- 200
- Registration Number
- NCT03662113
- Locations
- 🇨🇳
Children's hospital of Fudan university, Shanghai, Shanghai, China
Preliminarily Evaluate the Efficacy of Domperidone in Adult Chinese Participants With Functional Dyspepsia
- First Posted Date
- 2018-08-06
- Last Posted Date
- 2021-07-26
- Lead Sponsor
- Xian-Janssen Pharmaceutical Ltd.
- Target Recruit Count
- 160
- Registration Number
- NCT03617016
- Locations
- 🇨🇳
Capital Medical University, Beijing Friendship Hospital, Beijing, China
🇨🇳Peking Union Medical College Hospital, Beijing, China
🇨🇳Fujian Provincial Hospital, Fuzhou, China
Use of Domperidone to Increase Milk Production in Mothers With Newborns in Neonatology
- First Posted Date
- 2017-07-19
- Last Posted Date
- 2017-07-19
- Lead Sponsor
- Hospital de Clinicas de Porto Alegre
- Target Recruit Count
- 30
- Registration Number
- NCT03221855
- Locations
- 🇧🇷
Hospital de Clínicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil
Drug Development Updates
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