Domperidone
- Generic Name
- Domperidone
- Brand Names
- -
- Drug Type
- Small Molecule
- Chemical Formula
- C22H24ClN5O2
- CAS Number
- 57808-66-9
- Unique Ingredient Identifier
- 5587267Z69
- Background
A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
- Indication
For management of dyspepsia, heartburn, epigastric pain, nausea, and vomiting.
- Associated Conditions
- Diabetic Gastroparesis, Dyspepsia, Erosive Esophagitis, Gastrointestinal Symptoms, Non-erosive Reflux Esophagitis Disease (NERD), Upper gastrointestinal motility disorders
- Associated Therapies
- -
Domperidone in Refractory Gastroparesis
- First Posted Date
- 2008-09-26
- Last Posted Date
- 2017-08-18
- Lead Sponsor
- Yale University
- Target Recruit Count
- 44
- Registration Number
- NCT00760461
- Locations
- 🇺🇸
Yale Digestive Diseases 40 Temple St, Suite 1A, New Haven, Connecticut, United States
Domperidone for Gastroparesis in Solid Organ Transplantation
Not Applicable
Terminated
- Conditions
- Interventions
- First Posted Date
- 2007-11-01
- Last Posted Date
- 2015-07-10
- Lead Sponsor
- David J. Lederer, M.D.
- Target Recruit Count
- 6
- Registration Number
- NCT00552422
- Locations
- 🇺🇸
Columbia University Medical Center, New York, New York, United States
Effect of Domperidone on the Nutrient Composition of Preterm Mother's Breast Milk
Phase 2
Completed
- Conditions
- Interventions
- First Posted Date
- 2006-03-29
- Last Posted Date
- 2009-06-11
- Lead Sponsor
- IWK Health Centre
- Target Recruit Count
- 46
- Registration Number
- NCT00308334
- Locations
- 🇨🇦
IWK Health Centre, Halifax, Nova Scotia, Canada
Effectiveness of Domperidone to Increase Breastmilk Supply in Mothers With Low Supply
Phase 2
Terminated
- Conditions
- First Posted Date
- 2006-01-31
- Last Posted Date
- 2007-10-15
- Lead Sponsor
- Hamilton Health Sciences Corporation
- Target Recruit Count
- 45
- Registration Number
- NCT00284024
- Locations
- 🇨🇦
Stonechurch Family Health Centre, Hamilton, Ontario, Canada
Efficacy of Therapeutic Interventions for Orthostatic Hypotension in Parkinson's Disease and Multiple System Atrophy
Phase 1
Completed
- Conditions
- First Posted Date
- 2005-02-14
- Last Posted Date
- 2005-10-20
- Lead Sponsor
- Royal Brisbane and Women's Hospital
- Target Recruit Count
- 50
- Registration Number
- NCT00103597
- Locations
- 🇦🇺
Royal Brisbane and Women's Hospital, Brisbane, Queensland, Australia
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