Melatonin
- Generic Name
- Melatonin
- Brand Names
- Circadin, Slenyto, Melatonin Neurim
- Drug Type
- Small Molecule
- Chemical Formula
- C13H16N2O2
- CAS Number
- 73-31-4
- Unique Ingredient Identifier
- JL5DK93RCL
- Background
Melatonin is a biogenic amine that is found in animals, plants and microbes. Aaron B. Lerner of Yale University is credited for naming the hormone and for defining its chemical structure in 1958. In mammals, melatonin is produced by the pineal gland. The pineal gland is small endocrine gland, about the size of a rice grain and shaped like a pine cone (hence ...
- Indication
Used orally for jet lag, insomnia, shift-work disorder, circadian rhythm disorders in the blind (evidence for efficacy), and benzodiazepine and nicotine withdrawal. Evidence indicates that melatonin is likely effective for treating circadian rhythm sleep disorders in blind children and adults. It has received FDA orphan drug status as an oral medication for ...
- Associated Conditions
- Insomnia
- Associated Therapies
- -
Efficacy of Melatonin, Low-dose Quetiapine, or Placebo in Patients with Psychiatric Disorders and Comorbid Insomnia
- Conditions
- Interventions
- First Posted Date
- 2023-10-02
- Last Posted Date
- 2024-12-12
- Lead Sponsor
- Lone Baandrup
- Target Recruit Count
- 255
- Registration Number
- NCT06062953
- Locations
- 🇩🇰
Mental Health Center Copenhagen, Copenhagen NV, Denmark
The Premedication Properties of Oral Melatonin in Pediatrics Undergoing Therapeutic Cardiac Catheterization
- First Posted Date
- 2023-09-11
- Last Posted Date
- 2023-09-11
- Lead Sponsor
- Al-Azhar University
- Target Recruit Count
- 80
- Registration Number
- NCT06031961
- Locations
- 🇮🇶
Ministry of Health, Baghdad, Thi-Qar, Iraq
The Effect of Dexmedetomidine, Melatonin and Pregabalin
- Conditions
- Interventions
- First Posted Date
- 2023-04-25
- Last Posted Date
- 2023-04-25
- Lead Sponsor
- Egymedicalpedia
- Target Recruit Count
- 120
- Registration Number
- NCT05829148
- Locations
- 🇪🇬
Al-Azhar University hospitals, Cairo, Egypt
Nebulized Dexmedetomidine VS ODF Melatonin for Peri Operative Anxiety and Emergence Agitation in Pediatric Day Surgery
- Conditions
- Interventions
- First Posted Date
- 2023-03-13
- Last Posted Date
- 2023-03-13
- Lead Sponsor
- nada moahmed aboelrouse
- Target Recruit Count
- 50
- Registration Number
- NCT05766436
- Locations
- 🇪🇬
Ain shams university hospital, Cairo, Abbasia, Egypt
Gene and Protein Expression Profiles After Treatment of Actinic Keratoses
- Conditions
- Interventions
- First Posted Date
- 2023-02-23
- Last Posted Date
- 2023-02-23
- Lead Sponsor
- Ismail Gögenur
- Target Recruit Count
- 48
- Registration Number
- NCT05740969
- Locations
- 🇩🇰
Zealand University Hospital, Roskilde, Region Sjælland, Denmark
Melatonin for Treatment of Delirium in Critically Ill Adult Patients
- First Posted Date
- 2023-02-06
- Last Posted Date
- 2024-02-07
- Lead Sponsor
- Ciusss de L'Est de l'Île de Montréal
- Target Recruit Count
- 30
- Registration Number
- NCT05713877
- Locations
- 🇨🇦
Hopital Maisonneuve-Rosemont, Montréal, Quebec, Canada
Melatonin for Post Operative Delirium Prevention in Elderly Patients
- First Posted Date
- 2022-12-07
- Last Posted Date
- 2023-07-17
- Lead Sponsor
- Menoufia University
- Target Recruit Count
- 100
- Registration Number
- NCT05640934
- Locations
- 🇪🇬
Faculty of Medicine, Cairo, Shebin El-kom, Egypt
MELAtonin for Prevention of Postoperative Agitation and Emergence Delirium in Children
- Conditions
- Interventions
- First Posted Date
- 2022-09-15
- Last Posted Date
- 2024-11-15
- Lead Sponsor
- Rigshospitalet, Denmark
- Target Recruit Count
- 400
- Registration Number
- NCT05541276
- Locations
- 🇩🇰
Department of Anesthesiology, Juliane Marie Center, Rigshospitalet, Copenhagen, Capital Region, Denmark
Adjuvant Melatonin for Uveal Melanoma
- Conditions
- Interventions
- First Posted Date
- 2022-08-16
- Last Posted Date
- 2023-11-22
- Lead Sponsor
- Gustav Stalhammar
- Target Recruit Count
- 100
- Registration Number
- NCT05502900
- Locations
- 🇸🇪
St. Erik Eye Hospital, Stockholm, Sweden
Sedation and Nursing Management in EEG Recording in Children
- First Posted Date
- 2022-08-09
- Last Posted Date
- 2022-08-09
- Lead Sponsor
- Suleyman Demirel University
- Target Recruit Count
- 180
- Registration Number
- NCT05492812
- Locations
- 🇹🇷
Suleyman Demirel University, Isparta, Turkey
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.