Melatonin
- Generic Name
- Melatonin
- Brand Names
- Circadin, Slenyto, Melatonin Neurim
- Drug Type
- Small Molecule
- Chemical Formula
- C13H16N2O2
- CAS Number
- 73-31-4
- Unique Ingredient Identifier
- JL5DK93RCL
- Background
Melatonin is a biogenic amine that is found in animals, plants and microbes. Aaron B. Lerner of Yale University is credited for naming the hormone and for defining its chemical structure in 1958. In mammals, melatonin is produced by the pineal gland. The pineal gland is small endocrine gland, about the size of a rice grain and shaped like a pine cone (hence ...
- Indication
Used orally for jet lag, insomnia, shift-work disorder, circadian rhythm disorders in the blind (evidence for efficacy), and benzodiazepine and nicotine withdrawal. Evidence indicates that melatonin is likely effective for treating circadian rhythm sleep disorders in blind children and adults. It has received FDA orphan drug status as an oral medication for ...
- Associated Conditions
- Insomnia
- Associated Therapies
- -
Treatment of Nighttime Pruritus in Atopic Dermatitis
- Conditions
- Interventions
- First Posted Date
- 2018-09-28
- Last Posted Date
- 2023-08-15
- Lead Sponsor
- University of Nebraska
- Registration Number
- NCT03688464
CHOCOlate MeLatonin for AdolescenT MigrainE
- First Posted Date
- 2018-07-24
- Last Posted Date
- 2021-06-15
- Lead Sponsor
- Amy Gelfand
- Target Recruit Count
- 84
- Registration Number
- NCT03597529
- Locations
- 🇺🇸
University of California, San Francisco, (UCSF), San Francisco, California, United States
Safety and Efficacy of Melatonin in Patients with Multiple Progressive Primary Sclerosis
- Conditions
- Interventions
- First Posted Date
- 2018-05-30
- Last Posted Date
- 2024-11-15
- Target Recruit Count
- 50
- Registration Number
- NCT03540485
- Locations
- 🇪🇸
Hospital Vithas Nisa Sevilla, Seville, Spain
🇪🇸Virgen del Rocio University Hospital, Seville, Spain
🇪🇸Virgen Macarena Hospital, Seville, Spain
Melatonin Receptor Agonist and Peripheral Biological Markers
- Conditions
- First Posted Date
- 2018-02-13
- Last Posted Date
- 2022-10-10
- Lead Sponsor
- National Science Council, Taiwan
- Target Recruit Count
- 40
- Registration Number
- NCT03432091
Insulin Resistance in Patients After Carotid Revascularization
- First Posted Date
- 2018-02-05
- Last Posted Date
- 2018-02-05
- Lead Sponsor
- Peking Union Medical College Hospital
- Target Recruit Count
- 60
- Registration Number
- NCT03419767
- Locations
- 🇨🇳
Peking Union Medical College Hospital, Beijing, China
Acute Metabolic Effects of Melatonin Treatment
- First Posted Date
- 2017-07-02
- Last Posted Date
- 2020-03-25
- Lead Sponsor
- University of Aarhus
- Target Recruit Count
- 36
- Registration Number
- NCT03204877
- Locations
- 🇩🇰
Aarhus University Hospital, Aarhus, Denmark
Melatonin for Adolescent Migraine Prevention Study
- First Posted Date
- 2017-05-12
- Last Posted Date
- 2023-10-13
- Lead Sponsor
- Amy Gelfand
- Target Recruit Count
- 72
- Registration Number
- NCT03150797
- Locations
- 🇺🇸
UCLA Headache Research and Treatment Program, Los Angeles, California, United States
🇺🇸University of California, San Francisco, (UCSF), San Francisco, California, United States
Melatonin in Patients Under Carotid Endarterectomy
- First Posted Date
- 2017-04-14
- Last Posted Date
- 2017-11-07
- Lead Sponsor
- Peking Union Medical College Hospital
- Target Recruit Count
- 60
- Registration Number
- NCT03115034
- Locations
- 🇨🇳
Changwei Liu, Beijing, Beijing, China
Melatonin Use for Sleep Problems in Alcohol Dependent Patients
- First Posted Date
- 2017-02-06
- Last Posted Date
- 2019-02-04
- Lead Sponsor
- Centre for Addiction and Mental Health
- Target Recruit Count
- 60
- Registration Number
- NCT03043443
- Locations
- 🇨🇦
Centre for Addiction and Mental Health, Toronto, Ontario, Canada
🇨🇦Center for Addiction and Mental Health, Toronto, Ontario, Canada
Melatonin Use in the Intensive Care Elderly Population
- First Posted Date
- 2017-01-09
- Last Posted Date
- 2017-07-13
- Lead Sponsor
- MICE Trial Group
- Target Recruit Count
- 600
- Registration Number
- NCT03013790
- Locations
- 🇺🇸
Parkview Medical Center, Pueblo, Colorado, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.