Perindopril
- Generic Name
- Perindopril
- Brand Names
- Aceon, Coversyl, Prestalia, Viacoram
- Drug Type
- Small Molecule
- Chemical Formula
- C19H32N2O5
- CAS Number
- 82834-16-0
- Unique Ingredient Identifier
- Y5GMK36KGY
- Background
Perindopril is a nonsulfhydryl prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is rapidly metabolized in the liver to perindoprilat, its active metabolite, following oral administration. Perindoprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angiotensin I (ATI) ...
- Indication
For the treatment of mild to moderate essential hypertension, mild to moderate congestive heart failure, and to reduce the cardiovascular risk of individuals with hypertension or post-myocardial infarction and stable coronary disease.
- Associated Conditions
- Cardiovascular Events, Diabetic Nephropathy, Hypertension, Hypertension, Essential Hypertension, Myocardial Infarction, NYHA Class I Congestive heart failure, Stroke, Chronic heart failure with reduced ejection fraction (NYHA Class II), Chronic heart failure with reduced ejection fraction (NYHA Class III)
- Associated Therapies
- -
Timely Recovery After Subclinical Heart Failure
- First Posted Date
- 2024-04-02
- Last Posted Date
- 2024-04-02
- Lead Sponsor
- Academisch Ziekenhuis Maastricht
- Target Recruit Count
- 130
- Registration Number
- NCT06341101
- Locations
- 🇳🇱
AZMaastricht, Maastricht, Limburg, Netherlands
Precision Treatment With Angiotensin Converting Enzyme Inhibitor
- Conditions
- Interventions
- First Posted Date
- 2022-09-10
- Last Posted Date
- 2023-01-11
- Lead Sponsor
- Yonsei University
- Target Recruit Count
- 77
- Registration Number
- NCT05535595
- Locations
- 🇰🇷
Yonsei University Health System, Severance Hospital, Seoul, Korea, Republic of
Efficacy and Safety of Atorvastatin + Perindopril Fixed-Dose Combination S05167 in Adult Patients With Arterial Hypertension and Dyslipidemia
- Conditions
- Interventions
- First Posted Date
- 2020-10-19
- Last Posted Date
- 2023-10-18
- Lead Sponsor
- Institut de Recherches Internationales Servier
- Target Recruit Count
- 146
- Registration Number
- NCT04591808
- Locations
- 🇺🇦
Medical center ''CONSILIUM MEDICAL'', Kyiv, Ukraine
🇺🇦Private Small-Scale Enterprise Medical Center "Pulse", Vinnytsya, Ukraine
🇷🇺Saint Petersburg state budgetary institution of healthcare "City policlinic #109", Saint Petersburg, Russian Federation
Early Treatment of ARNI on Myocardial Remodeling and Progress
- First Posted Date
- 2020-04-13
- Last Posted Date
- 2020-04-14
- Lead Sponsor
- RenJi Hospital
- Target Recruit Count
- 280
- Registration Number
- NCT04342351
- Locations
- 🇨🇳
RenJi Hospital, Shanghai JiaoTong University, School of Medicine, Shanghai, Shanghai, China
Comparative Effects of Perindopril and Zofenopril on Blood Pressure Control and Oxidative Status Blacks Hypertensive Patients.
- Conditions
- Interventions
- First Posted Date
- 2020-02-05
- Last Posted Date
- 2020-02-05
- Lead Sponsor
- Yaounde Central Hospital
- Target Recruit Count
- 24
- Registration Number
- NCT04254042
- Locations
- 🇨🇲
Yaounde Central Hospital, Cardiology department, Yaounde, Cameroon
Evaluation of Losartan and Perindopril in Blacks Type 2 Diabetics Patients
- Conditions
- Interventions
- First Posted Date
- 2020-01-10
- Last Posted Date
- 2020-01-10
- Lead Sponsor
- Yaounde Central Hospital
- Target Recruit Count
- 23
- Registration Number
- NCT04222686
- Locations
- 🇨🇲
Yaounde Central Hospital, NAtional Obesity Center, Yaounde, Cameroon
Reversal of an Unfavorable Effect of Hydrochlorothiazide Compared to Angiotensin Converting Enzyme Inhibitor on Serum Uric Acid and Oxypurines Levels by Estrogen-progestin Therapy in Hypertensive Postmenopausal Women.
- Conditions
- Interventions
- First Posted Date
- 2019-04-19
- Last Posted Date
- 2019-04-22
- Lead Sponsor
- Anna Posadzy-Małaczyńska
- Target Recruit Count
- 180
- Registration Number
- NCT03921736
ACES - ACE Inhibitors Combined With Exercise for Seniors With Hypertension
- Conditions
- Interventions
- First Posted Date
- 2017-09-28
- Last Posted Date
- 2024-05-08
- Lead Sponsor
- University of Alabama at Birmingham
- Target Recruit Count
- 213
- Registration Number
- NCT03295734
- Locations
- 🇺🇸
UAB Center for Exercise Medicine, Birmingham, Alabama, United States
🇺🇸Translational Research Institute, Orlando, Florida, United States
Influence of Carboxypeptidase D (CPD) Gene on Body Weight and Fat Mass Reduction by Perindopril in Obese Subjects
- First Posted Date
- 2016-05-19
- Last Posted Date
- 2017-08-03
- Lead Sponsor
- Gene PreDiT
- Target Recruit Count
- 140
- Registration Number
- NCT02777489
- Locations
- 🇵🇹
Unidade de Saúde Familiar Escariz, Arouca, Portugal
🇵🇹Centro Hospitalar de São João (CHSJ), E.P.E, Porto, Portugal
🇵🇹Unidade de Cuidados de Saúde Personalizados Carvalhido, Porto, Portugal
Perindopril vs Ramipril for Persistence in MAU Reduction Study
- First Posted Date
- 2016-04-06
- Last Posted Date
- 2016-04-06
- Lead Sponsor
- Sunnybrook Health Sciences Centre
- Target Recruit Count
- 23
- Registration Number
- NCT02729441
- Locations
- 🇨🇦
Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
Drug Development Updates
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