MedPath

111In-J591

Generic Name
111In-J591

The Study of 177Lu-TLX591 Plus SOC Versus SOC Alone in Patients With mCRPC (ProstACT Global)

Phase 3
Recruiting
Conditions
Metastatic Castration-resistant Prostate Cancer
Interventions
First Posted Date
2024-07-25
Last Posted Date
2025-02-28
Lead Sponsor
Telix Pharmaceuticals (Innovations) Pty Limited
Target Recruit Count
430
Registration Number
NCT06520345
Locations
🇺🇸

Chao Family Comprehensive Cancer Centre, Orange, California, United States

🇺🇸

Biogenix Molecular LLC, Miami, Florida, United States

🇺🇸

United Theranostics, Glen Burnie, Maryland, United States

and more 9 locations

External Beam Therapy With Theranostic Radioligand Therapy for Oligometastatic Prostate Cancer (ProstACT TARGET)

Phase 2
Completed
Conditions
Prostate Cancer
Interventions
First Posted Date
2021-12-07
Last Posted Date
2024-12-19
Lead Sponsor
Telix Pharmaceuticals (Innovations) Pty Limited
Target Recruit Count
5
Registration Number
NCT05146973
Locations
🇦🇺

GenesisCare Murdoch, Perth, Western Australia, Australia

🇦🇺

GenesisCare North Shore, St Leonards, New South Wales, Australia

🇦🇺

GenesisCare St Andrews, Adelaide, Australia

and more 1 locations

177Lu-J591 and 177Lu-PSMA-617 Combination for mCRPC

Phase 1
Terminated
Conditions
Prostate Cancer
Interventions
First Posted Date
2018-06-04
Last Posted Date
2021-08-24
Lead Sponsor
Weill Medical College of Cornell University
Target Recruit Count
6
Registration Number
NCT03545165
Locations
🇺🇸

Weill Cornell Medical College, New York, New York, United States

Neoadjuvant J591 Treatment for Prostate Cancer

Phase 1
Completed
Conditions
Prostate Cancer
Interventions
First Posted Date
2016-02-29
Last Posted Date
2020-10-05
Lead Sponsor
Weill Medical College of Cornell University
Target Recruit Count
8
Registration Number
NCT02693860
Locations
🇺🇸

Weill Cornell Medical College, New York, New York, United States

J591 in Patients With Advanced Prostate Cancer and Unfavorable Circulating Tumor Cell Counts

Phase 1
Completed
Conditions
Prostate Cancer
Interventions
First Posted Date
2015-09-17
Last Posted Date
2023-04-06
Lead Sponsor
Weill Medical College of Cornell University
Target Recruit Count
10
Registration Number
NCT02552394
Locations
🇺🇸

Weill Cornell Medical College, New York, New York, United States

177Lu-J591 Antibody in Patients With Nonprostate Metastatic Solid Tumors

Phase 1
Completed
Conditions
Kidney Cancer
Gliomas
Head and Neck Cancer
Ovarian Cancer
Esophageal Cancer
Breast Cancer
Non-small Cell Lung Cancer
Colorectal Cancer
Pancreatic Cancer
Interventions
First Posted Date
2009-08-28
Last Posted Date
2022-02-02
Lead Sponsor
Weill Medical College of Cornell University
Target Recruit Count
20
Registration Number
NCT00967577
Locations
🇺🇸

Weill Cornell Medical College, New York, New York, United States

Docetaxel/Prednisone Plus Fractionated 177Lu- J591 Antibody for Metastatic, Castrate-resistant Prostate Cancer

Phase 1
Completed
Conditions
Prostate Cancer
Interventions
First Posted Date
2009-06-09
Last Posted Date
2021-05-20
Lead Sponsor
Weill Medical College of Cornell University
Target Recruit Count
15
Registration Number
NCT00916123
Locations
🇺🇸

Weill Cornell Medical College, New York, New York, United States

🇺🇸

University of North Carolina Chapel Hill Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina, United States

177Lu Radiolabeled Monoclonal Antibody HuJ591 (177Lu-J591) and Ketoconazole in Patients With Prostate Cancer

Phase 2
Active, not recruiting
Conditions
Prostate Cancer
Interventions
First Posted Date
2009-03-11
Last Posted Date
2025-04-30
Lead Sponsor
Weill Medical College of Cornell University
Target Recruit Count
55
Registration Number
NCT00859781
Locations
🇺🇸

Weill Cornell Medical College, New York, New York, United States

🇺🇸

The University of Kansas Cancer Center, Westwood, Kansas, United States

🇺🇸

USC/Norris Comprehensive cancer center, Los Angeles, California, United States

and more 6 locations
© Copyright 2025. All Rights Reserved by MedPath