Doripenem

Generic Name
Doripenem
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C15H24N4O6S2
CAS Number
148016-81-3
Unique Ingredient Identifier
BHV525JOBH
Background

Doripenem is a broad-spectrum, carbapenem antibiotic marketed under the brand name Doribax by Janssen. Doripenem injection was approved by the FDA in 2007 to treat complicated urinary tract and intra-abdominal infections. In a clinical trial of doripenem treatment in ventilator associated pneumonia (vs. imipenem and cilastatin), it was found that doripenem c...

Indication

用于敏感的革兰阳性菌、阴性菌和厌氧菌所致的呼吸系统、尿道、皮肤软组织、脑组织感染、败血症、细菌性心内膜炎等全身性严重感染,各种外科手术后感染等。

Associated Conditions
Bacterial Infections, Catheter-related Bloodstream Infection (CRBSI) NOS, Complicated Intra-Abdominal Infections (cIAIs), Complicated Urinary Tract Infection, Pyelonephritis
Associated Therapies
-

Doripenem in the Treatment of Complicated Lower Urinary Tract Infection or Pyelonephritis

Phase 3
Completed
Conditions
First Posted Date
2005-09-21
Last Posted Date
2011-06-10
Lead Sponsor
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Target Recruit Count
403
Registration Number
NCT00210990

Doripenem in the Treatment of Hospital-Acquired Pneumonia

Phase 3
Completed
Conditions
First Posted Date
2005-09-21
Last Posted Date
2011-06-10
Lead Sponsor
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Target Recruit Count
240
Registration Number
NCT00211003

Doripenem in the Treatment of Complicated Intra-Abdominal Infections

First Posted Date
2005-09-21
Last Posted Date
2011-06-10
Lead Sponsor
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Target Recruit Count
478
Registration Number
NCT00210938
© Copyright 2024. All Rights Reserved by MedPath