Azilsartan medoxomil

Generic Name
Azilsartan medoxomil
Brand Names
Edarbyclor, Edarbi
Drug Type
Small Molecule
Chemical Formula
C30H24N4O8
CAS Number
863031-21-4
Unique Ingredient Identifier
LL0G25K7I2
Background

Azilsartan medoxomil is a prodrug that is broken down to azilsartan, which belongs in the angiotensin-receptor blocking (ARB) drug class. It is a selective AT1 subtype angiotensin II receptor antagonist. Azilsartan medoxomil is a relatively recently-developed antihypertensive drug that was first approved by the FDA in February 2011. Many guidelines recommend...

Indication

Azilsartan medoxomil is indicated for the treatment of hypertension to lower blood pressure in patients over 18 years of age. It may be used either alone or in combination with other antihypertensive agents. Some antihypertensive drugs have lesser effects on blood pressure in black patients.
...

Associated Conditions
Albuminuria, Hypertension, Atrial Fibrillation
Associated Therapies
-
Clinical Trials
Related News

Azilsartan Medoxomil (TAK-491) Compared to Placebo in Korean Adults With Hypertension

First Posted Date
2014-07-30
Last Posted Date
2016-12-19
Lead Sponsor
Takeda
Target Recruit Count
328
Registration Number
NCT02203916

Azilsaltan Tablets (Azilva Tablets) Special Drug Use Surveillance "Hypertension Complicated by Diabetes "

Completed
Conditions
Hypertension
Interventions
Drug: Azilsartan
First Posted Date
2014-03-31
Last Posted Date
2019-03-21
Lead Sponsor
Takeda
Target Recruit Count
387
Registration Number
NCT02100319

Azilsartan Tablets Special Drug Use Surveillance: Long-term Use

Completed
Conditions
Hypertension
Interventions
Drug: Azilsartan
First Posted Date
2014-03-19
Last Posted Date
2019-01-15
Lead Sponsor
Takeda
Target Recruit Count
3437
Registration Number
NCT02092025

A Study to Explore the Effects of Azilsartan Compared to Telmisartan on Insulin Resistance of Patients With Essential Hypertension on Type 2 Diabetes Mellitus by HOMA-R

First Posted Date
2014-03-06
Last Posted Date
2017-08-02
Lead Sponsor
Takeda
Target Recruit Count
33
Registration Number
NCT02079805

Azilsartan Circadian and Sleep Pressure

Not Applicable
Completed
Conditions
Hypertension
Interventions
Drug: Amlodipine
Drug: Azilsartan
First Posted Date
2013-01-07
Last Posted Date
2015-12-28
Lead Sponsor
Sogo Rinsho Médéfi Co., Ltd.
Target Recruit Count
957
Registration Number
NCT01762501
Locations
🇯🇵

Seikei-kai New Tokyo Hospital, Matsudo, Chiba, Japan

🇯🇵

Hoshi General Hospital, Koriyama, Fukushima, Japan

🇯🇵

Keijukai Itabashi Clinic, Koga, Ibaraki, Japan

and more 89 locations

New Angiotensin II Receptor Blocker Azilsartan Study for Stronger Blood Pressure Lowering

Phase 4
Completed
Conditions
Hypertension
Interventions
Drug: Valsartan
Drug: Azilsartan
First Posted Date
2012-06-01
Last Posted Date
2013-10-30
Lead Sponsor
Nara Medical University
Target Recruit Count
70
Registration Number
NCT01609959
Locations
🇯🇵

First Department of Nara Medical University, Kashihara, Nara, Japan

Efficacy and Safety of Azilsartan Medoxomil Used in Combination With Metformin in Participants With Hypertension and Diabetes

Phase 3
Terminated
Conditions
Diabetes
Hypertension
Interventions
Drug: Placebo
Drug: Azilsartan medoxomil
First Posted Date
2011-12-21
Last Posted Date
2015-05-06
Lead Sponsor
Takeda
Target Recruit Count
105
Registration Number
NCT01496430

Efficacy and Safety of Azilsartan in Participants With Mild to Moderate Uncomplicated Essential Hypertension

First Posted Date
2011-02-03
Last Posted Date
2011-02-03
Lead Sponsor
Takeda
Target Recruit Count
926
Registration Number
NCT01289132

Efficacy and Safety of Azilsartan Medoxomil Combined With Chlorthalidone in Participants With Moderate to Severe Hypertension

First Posted Date
2009-02-19
Last Posted Date
2012-02-07
Lead Sponsor
Takeda
Target Recruit Count
1711
Registration Number
NCT00847626

Efficacy and Safety Study of Azilsartan Medoxomil Compared to Ramipril for Treating Essential Hypertension

Phase 3
Completed
Conditions
Hypertension
Interventions
Drug: Ramipril
Drug: Azilsartan medoxomil
First Posted Date
2008-09-26
Last Posted Date
2012-11-15
Lead Sponsor
Takeda
Target Recruit Count
885
Registration Number
NCT00760214
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