Istradefylline, or KW6002, was developed by Kyowa Hakko Kirin in Japan for the treatment of Parkinson's disease as an adjunct to standard therapy. Unlike standard dopaminergic therapies for Parkinson's, Istradefylline targets adenosine A receptors in the basal ganglia. This region of the brain is highly involved in motor control.
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Istradefylline is indicated in adjunct to levodopa and carbidopa in the treatment of Parkinson's disease.
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