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GNK-301 is a monoclonal antibody directed against the envelope protein (K Env) of Human Endogenous Retrovirus K (HERV K). K Env is a highly neurotoxic retroviral protein found in the spinal fluid of more than 75% of people with ALS and has been shown to produce the neurodegenerative findings of ALS in laboratory animals and in human motor neuron cell culture; GNK-301 binds K Env and blocks these neurotoxic effects.
每项发明一条,涵盖美国、欧洲、PCT 与中国的同族专利。
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专利文献通常使用化学名或研发代号指代药物,而非通用名;且专利申请在提交约 18 个月后才公开,较新的药物可能尚未出现在这里。