Flucytosine
- Generic Name
- Flucytosine
- Brand Names
- Ancobon
- Drug Type
- Small Molecule
- Chemical Formula
- C4H4FN3O
- CAS Number
- 2022-85-7
- Unique Ingredient Identifier
- D83282DT06
- Background
A fluorinated cytosine analog that is used as an antifungal agent.
- Indication
For the treatment (in combination with amphotericin B) of serious infections caused by susceptible strains of Candida (septicemia, endocarditis and urinary system infections) and/or Cryptococcus (meningitis and pulmonary infections).
- Associated Conditions
- Candidiasis, Candidiasis, Systemic, Cryptococcal infections, Fungal Infections, Fungal endocarditis, Meningitis, Fungal, Septicemia, Urinary tract infection fungal, Disseminated Cryptococcosis
- Associated Therapies
- -
Multi-center Comparison of Fluconazole (UK-49,858) and Amphotericin B as Treatment for Acute Cryptococcal Meningitis
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2011-03-14
- Target Recruit Count
- 120
- Registration Number
- NCT00000708
- Locations
- 🇺🇸
Univ of Miami School of Medicine, Miami, Florida, United States
🇺🇸Julio Arroyo, West Columbia, South Carolina, United States
🇺🇸Tulane Univ School of Medicine, New Orleans, Louisiana, United States
Dexamethasone in Cryptococcal Meningitis
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2021-10-28
- Target Recruit Count
- 36
- Registration Number
- NCT00000776
- Locations
- 🇺🇸
Northwestern Univ Med School, Chicago, Illinois, United States
🇺🇸Cook County Hosp, Chicago, Illinois, United States
🇺🇸Univ of Miami School of Medicine, Miami, Florida, United States
Safety and Antifungal Activity of Recombinant Interferon-Gamma 1b (rIFN-Gamma 1b) Given With Standard Therapy in Patients With Cryptococcal Meningitis
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2009-06-03
- Lead Sponsor
- InterMune
- Target Recruit Count
- 60
- Registration Number
- NCT00012467
- Locations
- 🇺🇸
Houston Veterans Administration Med Ctr, Houston, Texas, United States
🇺🇸Univ of Texas / Med School at Houston, Houston, Texas, United States
🇵🇪Instituto de Medicina Tropical, Lima, Peru
Drug Development Updates
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