Prednisone

Generic Name
Prednisone
Brand Names
Deltasone, Rayos, Winpred
Drug Type
Small Molecule
Chemical Formula
C21H26O5
CAS Number
53-03-2
Unique Ingredient Identifier
VB0R961HZT
Background

A synthetic anti-inflammatory glucocorticoid derived from cortisone. It is biologically inert and converted to prednisolone in the liver.

Prednisone was granted FDA approval on 21 February 1955.

Indication

Prednisone is indicated as an anti-inflammatory or immunosuppressive drug for allergic, dermatologic, gastrointestinal, hematologic, ophthalmologic, nervous system, renal, respiratory, rheumatologic, infectious, endocrine, or neoplastic conditions as well as in organ transplant.

Associated Conditions
Acne Vulgaris, Acute Exacerbation of Chronic Obstructive Pulmonary Disease, Acute Gouty Arthritis, Acute Leukemia, Aggressive Lymphoma, Allergic Bronchopulmonary Aspergillosis, Allergic Conjunctivitis (AC), Allergic Rhinitis (AR), Allergic corneal marginal ulcers, Alveolitis, Extrinsic Allergic, Ankylosing Spondylitis (AS), Aspiration Pneumonitis, Asthma, Atopic Dermatitis, Autoimmune Hepatitis, Bell's Palsy, Berylliosis, Bullous dermatitis herpetiformis, Chorioretinitis, Congenital Adrenal Hyperplasia (CAH), Congenital Hypoplastic Anemia, Contact Dermatitis, Disseminated tuberculosis, Drug hypersensitivity reaction, Edema of the cerebrum, Epicondylitis, Erythroblastopenia, Giant Cell Arteritis (GCA), Hypercalcemia of Malignancy, Idiopathic Pulmonary Fibrosis (IPF), Immune Thrombocytopenia (ITP), Iridocyclitis, Iritis, Keratitis, Leukemias, Loeffler's syndrome, Lymphoma, Meningitis caused by Mycobacterium Tuberculosis, Metastatic Castration-Resistant Prostate Cancer (mCRPC), Mycosis Fungoides (MF), Ocular Inflammation, Ophthalmia, Sympathetic, Optic Neuritis, Pain caused by Herpes zoster, Pemphigus, Pericarditis, Pneumocystis Jirovecii Pneumonia, Polymyalgia Rheumatica (PMR), Polymyositis, Posterior Uveitis, Primary adrenocortical insufficiency, Psoriatic Arthritis, Pure Red Cell Aplasia, Regional Enteritis, Relapsing Polychondritis, Rheumatoid Arthritis, Rheumatoid Arthritis, Juvenile, Secondary adrenocortical insufficiency, Secondary thrombocytopenia, Serum Sickness, Severe Seborrheic Dermatitis, Sjogren's Syndrome (SS), Solid Organ Transplant Rejection, Stevens-Johnson Syndrome, Systemic Lupus Erythematosus, Takayasu Arteritis, Thyroid Eye Disease, Thyroiditis, Thyrotoxicosis, Trichinosis, Ulcerative Colitis, Uveitis, Vasculitis, Acquired immune hemolytic anemia, Acute Bursitis, Acute Crohn's Disease (CD), Acute Multiple sclerosis exacerbation, Acute rheumatic carditis, Anterior eye segment inflammation, Exfoliative erythroderma, Fulminating Tuberculosis, Idiopathic Bronchiolitis obliterans with organizing pneumonia, Idiopathic eosinophilic pneumonias, Non-suppurative Thyroiditis, Severe Psoriasis, Subacute Bursitis, Symptomatic Sarcoidosis, Synovitis of osteoarthritis, Systemic Dermatomyositis, Varicella-zoster virus acute retinal necrosis
Associated Therapies
Palliative Treatment

Combination Chemotherapy in Treating Patients With Previously Untreated Advanced Hodgkin's Lymphoma

Phase 3
Conditions
First Posted Date
2003-01-27
Last Posted Date
2013-09-20
Lead Sponsor
Mount Vernon Cancer Centre at Mount Vernon Hospital
Target Recruit Count
850
Registration Number
NCT00041210
Locations
🇬🇧

Pinderfields General Hospital, Wakefield, Scotland, United Kingdom

🇬🇧

Aintree University Hospital, Liverpool, England, United Kingdom

🇬🇧

City Hospital - Birmingham, West Bromwich, England, United Kingdom

and more 34 locations

Combination Chemotherapy Plus Filgrastim With or Without Rituximab in Treating Older Patients With Non-Hodgkin's Lymphoma

Phase 3
Conditions
First Posted Date
2003-01-27
Last Posted Date
2013-09-17
Lead Sponsor
Commissie Voor Klinisch Toegepast Onderzoek
Target Recruit Count
400
Registration Number
NCT00028717
Locations
🇳🇱

Academisch Medisch Centrum at University of Amsterdam, Amsterdam, Netherlands

🇳🇱

Medisch Spectrum Twente, Enschede, Netherlands

🇳🇱

Daniel Den Hoed Cancer Center at Erasmus Medical Center, Rotterdam, Netherlands

and more 10 locations

SWOG-9704 Chemoradiotherapy and Peripheral Stem Cell Transplantation Compared With Combination Chemotherapy in Treating Patients With Non-Hodgkin's Lymphoma

First Posted Date
2003-01-27
Last Posted Date
2021-02-02
Lead Sponsor
SWOG Cancer Research Network
Target Recruit Count
397
Registration Number
NCT00004031
Locations
🇨🇦

Moncton Hospital, Moncton, New Brunswick, Canada

🇺🇸

Oregon Health & Science University, Portland, Oregon, United States

🇨🇦

Centre Hospitalier Universitaire de Quebec, Quebec City, Quebec, Canada

and more 12 locations

S0204 Thalidomide, Chemotherapy, and Peripheral Stem Cell Transplant in Treating Patients With Multiple Myeloma

First Posted Date
2003-01-27
Last Posted Date
2016-12-08
Lead Sponsor
SWOG Cancer Research Network
Target Recruit Count
147
Registration Number
NCT00040937
Locations
🇺🇸

Charles B. Eberhart Cancer Center at DeKalb Medical Center, Decatur, Georgia, United States

🇺🇸

Community Medical Center, Missoula, Montana, United States

🇺🇸

Montana Cancer Center at St. Patrick Hospital and Health Sciences Center, Missoula, Montana, United States

and more 138 locations

TITLE:Less Intensive Therapy for Children With Non-Hodgkin's Lymphoma

First Posted Date
2003-01-27
Last Posted Date
2014-07-24
Lead Sponsor
Children's Oncology Group
Target Recruit Count
1148
Registration Number
NCT00002757
Locations
🇫🇷

Institut Gustave Roussy, Villejuif, France

🇬🇧

Children's Hospital - Sheffield, Sheffield, England, United Kingdom

Comparison of Two Combination Chemotherapy Regimens in Treating Adults With Previously Untreated Leukemia or Lymphoma

First Posted Date
2003-01-27
Last Posted Date
2016-02-22
Lead Sponsor
Memorial Sloan Kettering Cancer Center
Target Recruit Count
170
Registration Number
NCT00002766
Locations
🇺🇸

Stanford Cancer Center at Stanford University Medical Center, Stanford, California, United States

🇺🇸

Jonsson Comprehensive Cancer Center, UCLA, Los Angeles, California, United States

🇺🇸

Winship Cancer Institute of Emory University, Atlanta, Georgia, United States

and more 4 locations

Comparison of Two Combination Chemotherapy Regimens in Treating Patients With Stage III or Stage IV Hodgkin's Lymphoma

First Posted Date
2003-01-27
Last Posted Date
2023-11-09
Lead Sponsor
European Organisation for Research and Treatment of Cancer - EORTC
Target Recruit Count
552
Registration Number
NCT00049595
Locations
🇳🇱

Onze Lieve Vrouwe Gasthuis, Amsterdam, Netherlands

🇧🇪

Clinique Universitaire De Mont-Godinne, Yvoir, Belgium

🇦🇺

Canberra Hospital, Garran, Australian Capital Territory, Australia

and more 137 locations

Combination Chemotherapy in Treating Patients With Advanced Hodgkin's Lymphoma

First Posted Date
2003-01-27
Last Posted Date
2020-08-12
Lead Sponsor
Stanford University
Target Recruit Count
50
Registration Number
NCT00002715
Locations
🇺🇸

Stanford Cancer Center at Stanford University Medical Center, Stanford, California, United States

Combination Chemotherapy in Treating Children With Non-Hodgkin's Lymphoma

Phase 3
Completed
Conditions
First Posted Date
2003-01-27
Last Posted Date
2021-02-21
Lead Sponsor
UNICANCER
Target Recruit Count
179
Registration Number
NCT00003650
Locations
🇫🇷

Centre Leon Berard, Lyon, France

Methotrexate With or Without Cyclophosphamide in Treating Patients With Lymphocytic Leukemia

First Posted Date
2003-01-27
Last Posted Date
2023-07-05
Lead Sponsor
Eastern Cooperative Oncology Group
Target Recruit Count
59
Registration Number
NCT00003910
Locations
🇺🇸

Minnesota Oncology Hematology, PA - Woodbury, Woodbury, Minnesota, United States

🇺🇸

Robert H. Lurie Comprehensive Cancer Center at Northwestern University, Chicago, Illinois, United States

🇺🇸

McFarland Clinic, PC, Ames, Iowa, United States

and more 65 locations
© Copyright 2024. All Rights Reserved by MedPath