Proparacaine

Generic Name
Proparacaine
Brand Names
Alcaine, Lenalidomide Krka d.d. Novo mesto (previously Lenalidomide Krka), Revlimid, Lenalidomide Mylan, Lenalidomide Krka (previously Lenalidomide Krka d.d. Novo mesto), Lenalidomide Accord
Drug Type
Small Molecule
Chemical Formula
C16H26N2O3
CAS Number
499-67-2
Unique Ingredient Identifier
B4OB0JHI1X
Background

Proparacaine is a topical anesthetic drug of the amino ester group. It is found in ophthalmic solutions at a concentration of 0.5% as the hydrochloride salt.

Indication

Used as a local (ophthalmic) anesthetic.

Associated Conditions
Chronic Lymphocytic Leukemia (CLL) - Refractory, Follicular Lymphoma ( FL), Mantle Cell Lymphoma (MCL), Marginal Zone Lymphoma (MZL), Multiple Myeloma (MM), Myelodysplastic Syndrome, Primary Amyloidosis, Refractory Diffuse Large B Cell Lymphoma (DLBCL)
Associated Therapies
Local Anaesthesia therapy

Lenalidomide and Dacarbazine (DTIC) in Patients With Metastatic Melanoma

Phase 1
Completed
Conditions
Interventions
First Posted Date
2006-12-18
Last Posted Date
2016-04-29
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
28
Registration Number
NCT00412581
Locations
🇺🇸

U.T.M.D. Anderson Cancer Center, Houston, Texas, United States

Bevacizumab, Lenalidomide, and Dexamethasone in Patients With Relapsed or Refractory Stage II or III Multiple Myeloma

First Posted Date
2006-12-13
Last Posted Date
2017-09-01
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
39
Registration Number
NCT00410605
Locations
🇺🇸

University of Wisconsin Hospital and Clinics, Madison, Wisconsin, United States

🇺🇸

University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, United States

Lenalidomide in Treating Patients With Advanced or Unresectable Kidney Cancer

Phase 2
Completed
Conditions
Interventions
First Posted Date
2006-11-23
Last Posted Date
2017-04-20
Lead Sponsor
The Cleveland Clinic
Target Recruit Count
26
Registration Number
NCT00403169
Locations
🇺🇸

Case Comprehensive Cancer Center, Cleveland, Ohio, United States

Lenalidomide and Temsirolimus in Treating Patients With Previously Treated Multiple Myeloma

First Posted Date
2006-11-10
Last Posted Date
2013-09-30
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
25
Registration Number
NCT00398515
Locations
🇺🇸

Ohio State University Medical Center, Columbus, Ohio, United States

Bortezomib, Lenalidomide, and Dexamethasone Combination Therapy for Patients With Relapsed or Relapsed and Refractory Multiple Myeloma

First Posted Date
2006-09-19
Last Posted Date
2016-11-17
Lead Sponsor
Dana-Farber Cancer Institute
Target Recruit Count
65
Registration Number
NCT00378209
Locations
🇺🇸

Massachusetts General Hospital, Boston, Massachusetts, United States

🇺🇸

Dana-Farber Cancer Institute, Boston, Massachusetts, United States

Bortezomib, Lenalidomide and Dexamethasone Combination Therapy in Patients With Newly Diagnosed Multiple Myeloma

Phase 1
Active, not recruiting
Conditions
Interventions
First Posted Date
2006-09-19
Last Posted Date
2024-11-27
Lead Sponsor
Dana-Farber Cancer Institute
Target Recruit Count
68
Registration Number
NCT00378105
Locations
🇺🇸

Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States

🇺🇸

Massachusetts General Hospital, Boston, Massachusetts, United States

🇺🇸

Dana-Farber Cancer Institute, Boston, Massachusetts, United States

Lenalidomide for Patients With Myelofibrosis (MF)

Phase 2
Completed
Conditions
Interventions
First Posted Date
2006-07-17
Last Posted Date
2019-07-23
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
40
Registration Number
NCT00352794
Locations
🇺🇸

University of Texas MD Anderson Cancer Center, Houston, Texas, United States

Lenalidomide and Azacitidine in Treating Patients With Advanced Myelodysplastic Syndromes

First Posted Date
2006-07-14
Last Posted Date
2018-09-19
Lead Sponsor
Mikkael Sekeres MD
Target Recruit Count
37
Registration Number
NCT00352001
Locations
🇺🇸

H. Lee Moffitt Cancer Center and Research Institute at University of South Florida, Tampa, Florida, United States

🇺🇸

University of California at Los Angeles, Los Angeles, California, United States

🇺🇸

Cleveland Clinic Taussig Cancer Instititute, Case Comprehensive Cancer Center, Cleveland, Ohio, United States

Lenalidomide in Treating Older Patients With Acute Myeloid Leukemia

First Posted Date
2006-07-14
Last Posted Date
2022-02-11
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
41
Registration Number
NCT00352365
Locations
🇺🇸

Berdeaux, Donald MD (UIA Investigator), Great Falls, Montana, United States

🇺🇸

Great Falls Clinic, Great Falls, Montana, United States

🇺🇸

Bozeman Deaconess Cancer Center, Bozeman, Montana, United States

and more 51 locations

A Phase II Clinical Trial of Lenalidomide for T-cell Non-Hodgkin's Lymphoma

Phase 2
Completed
Conditions
First Posted Date
2006-05-09
Last Posted Date
2016-03-16
Lead Sponsor
AHS Cancer Control Alberta
Target Recruit Count
40
Registration Number
NCT00322985
Locations
🇨🇦

Cancer Care Manitoba, Winnipeg, Manitoba, Canada

🇨🇦

Queen Elizabeth II, Health Services Centre, Halifax,, Nova Scotia, Canada

🇨🇦

Ottawa Hospital General Campus, Ottawa, Ontario, Canada

and more 2 locations
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