Proparacaine

Generic Name
Proparacaine
Brand Names
Alcaine, Lenalidomide Krka d.d. Novo mesto (previously Lenalidomide Krka), Revlimid, Lenalidomide Mylan, Lenalidomide Krka (previously Lenalidomide Krka d.d. Novo mesto), Lenalidomide Accord
Drug Type
Small Molecule
Chemical Formula
C16H26N2O3
CAS Number
499-67-2
Unique Ingredient Identifier
B4OB0JHI1X
Background

Proparacaine is a topical anesthetic drug of the amino ester group. It is found in ophthalmic solutions at a concentration of 0.5% as the hydrochloride salt.

Indication

Used as a local (ophthalmic) anesthetic.

Associated Conditions
Chronic Lymphocytic Leukemia (CLL) - Refractory, Follicular Lymphoma ( FL), Mantle Cell Lymphoma (MCL), Marginal Zone Lymphoma (MZL), Multiple Myeloma (MM), Myelodysplastic Syndrome, Primary Amyloidosis, Refractory Diffuse Large B Cell Lymphoma (DLBCL)
Associated Therapies
Local Anaesthesia therapy

Lenalidomide and Melphalan in Treating Patients With Previously Untreated Multiple Myeloma

First Posted Date
2006-03-22
Last Posted Date
2023-08-04
Lead Sponsor
NCIC Clinical Trials Group
Target Recruit Count
51
Registration Number
NCT00305812
Locations
🇨🇦

Allan Blair Cancer Centre at Pasqua Hospital, Regina, Saskatchewan, Canada

🇨🇦

Nova Scotia Cancer Centre, Halifax, Nova Scotia, Canada

🇨🇦

Hopital Notre-Dame du CHUM, Montreal, Quebec, Canada

and more 11 locations

Lenalidomide and Rituximab in the Treatment of Relapsed Mantle Cell Lymphoma (MCL) and Diffuse Large B-Cell Lymphoma

Phase 1
Completed
Conditions
Interventions
First Posted Date
2006-02-22
Last Posted Date
2020-02-24
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
54
Registration Number
NCT00294632
Locations
🇺🇸

University of Texas MD Anderson Cancer Center, Houston, Texas, United States

REVLIMID® (Lenalidomide) for Therapy of Radioiodine-Unresponsive Papillary and Follicular Thyroid Carcinomas

Phase 2
Completed
Conditions
Interventions
First Posted Date
2006-02-06
Last Posted Date
2020-06-12
Lead Sponsor
Kenneth Ain
Target Recruit Count
25
Registration Number
NCT00287287
Locations
🇺🇸

University of Kentucky Markey Cancer Center, Lexington, Kentucky, United States

Lenalidomide (Revlimid) in Chronic Lymphocytic Leukemia (CLL)

Phase 2
Completed
Conditions
Interventions
First Posted Date
2005-12-20
Last Posted Date
2012-08-07
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
45
Registration Number
NCT00267059
Locations
🇺🇸

UT MD Anderson Cancer Center, Houston, Texas, United States

Lenalidomide and Docetaxel in Treating Patients With Advanced Solid Tumors

First Posted Date
2005-11-15
Last Posted Date
2010-06-11
Lead Sponsor
Case Comprehensive Cancer Center
Target Recruit Count
33
Registration Number
NCT00253344
Locations
🇺🇸

Ireland Cancer Center at University Hosptials Case Medical Center, Case Comprehensive Cancer Center, Cleveland, Ohio, United States

Rituximab and/or Lenalidomide in Treating Patients With Follicular Non-Hodgkin's Lymphoma That is Not Refractory to Rituximab

Phase 2
Completed
Conditions
Interventions
First Posted Date
2005-10-13
Last Posted Date
2017-03-15
Lead Sponsor
Alliance for Clinical Trials in Oncology
Target Recruit Count
97
Registration Number
NCT00238238
Locations
🇺🇸

Menorah Medical Center, Overland Park, Kansas, United States

🇺🇸

Rebecca and John Moores UCSD Cancer Center, La Jolla, California, United States

🇺🇸

Memorial Hospital, Carthage, Illinois, United States

and more 76 locations

Lenalidomide and Prednisone in Treating Patients With Myelofibrosis

First Posted Date
2005-09-28
Last Posted Date
2014-05-21
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
48
Registration Number
NCT00227591
Locations
🇺🇸

Eastern Cooperative Oncology Group, Boston, Massachusetts, United States

Lenalidomide (Revlimid®, CC-5013) in Subjects With Relapsed or Refractory Indolent Non-Hodgkin's Lymphoma

Phase 2
Completed
Conditions
Interventions
First Posted Date
2005-09-16
Last Posted Date
2013-11-28
Lead Sponsor
Celgene Corporation
Target Recruit Count
43
Registration Number
NCT00179673
Locations
🇺🇸

Alta Bates Cancer Center, Berkeley, California, United States

🇺🇸

Pacific Coast Hematology/Oncology Medical Group, Onc., Fountain Valley, California, United States

🇺🇸

Swedish Cancer Institute, Seattle, Washington, United States

and more 12 locations

Safety And Efficacy Of Lenalidomide In Patients With Relapsed Or Refractory Aggressive Non-Hodgkin's Lymphoma (NHL)

Phase 2
Completed
Conditions
Interventions
First Posted Date
2005-09-16
Last Posted Date
2016-01-21
Lead Sponsor
Celgene Corporation
Target Recruit Count
50
Registration Number
NCT00179660
Locations
🇺🇸

UC David Cancer Center, Sacramento, California, United States

🇺🇸

New York Medical Center, MBCCOP, Bronx, New York, United States

🇺🇸

Sylvester Cancer CenterUniversity Of Miami, Miami, Florida, United States

and more 5 locations

Expanded Access Program:Lenalidomide With or Without Dexamethasone In Previously Treated Subjects With Multiple Myeloma

Phase 3
Completed
Conditions
Interventions
First Posted Date
2005-09-16
Last Posted Date
2010-03-16
Lead Sponsor
Celgene Corporation
Target Recruit Count
1913
Registration Number
NCT00179647
Locations
🇺🇸

University of Texas Southwestern Medical Center, Dallas, Texas, United States

🇺🇸

Mayo Clinic, Scottsdale, Arizona, United States

🇺🇸

Cedar Sinai Medical CenterDept of Medicine, Los Angeles, California, United States

and more 66 locations
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