D-Glutamine
- Generic Name
- D-Glutamine
- Brand Names
- Endari
- Drug Type
- Small Molecule
- Chemical Formula
- C5H10N2O3
- CAS Number
- 5959-95-5
- Unique Ingredient Identifier
- 63HB36CA2Y
- Background
A non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes. It is synthesized from glutamic acid and ammonia. It is the principal carrier of nitrogen in the body and is an important energy source for many cells.
- Indication
Used for nutritional supplementation, also for treating dietary shortage or imbalance.
Used to reduce the acute complications of sickle cell disease in adult and pediatric patients 5 years of age and older .
- Associated Conditions
- Osteoporosis, Acute Complications of Sickle Cell Disease
- Associated Therapies
- -
Glutamine Therapy for Hemolysis-Associated Pulmonary Hypertension
- Conditions
- Interventions
- First Posted Date
- 2010-01-14
- Last Posted Date
- 2021-06-10
- Lead Sponsor
- UCSF Benioff Children's Hospital Oakland
- Target Recruit Count
- 13
- Registration Number
- NCT01048905
- Locations
- 🇺🇸
Children's Hospital & Research Center Oakland, Oakland, California, United States
Scandinavian Intensive Care Unit (ICU) Glutamine Study
- First Posted Date
- 2009-06-17
- Last Posted Date
- 2009-06-17
- Lead Sponsor
- Scandinavian Critical Care Trials Group
- Target Recruit Count
- 1000
- Registration Number
- NCT00922714
- Locations
- 🇸🇪
Intensive Care Unit, Karolinska University Hospital Huddinge, Stockholm, Sweden
A Randomized Double-Blind Control-Comparison Crossover Trial of Oral Glutamine to Suppress Frequently Recurrent Herpes Labialis
- Conditions
- First Posted Date
- 2009-06-04
- Last Posted Date
- 2012-06-11
- Target Recruit Count
- 11
- Registration Number
- NCT00913692
- Locations
- 🇺🇸
National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States
Anaplerotic Therapy in Propionic Acidemia
- Conditions
- Interventions
- First Posted Date
- 2008-03-28
- Last Posted Date
- 2015-01-21
- Lead Sponsor
- Nicola Longo
- Target Recruit Count
- 3
- Registration Number
- NCT00645879
- Locations
- 🇺🇸
University of Utah, Department of Pediatrics, Salt Lake City, Utah, United States
L-Glutamine Therapy for Sickle Cell Anemia
- First Posted Date
- 2008-01-04
- Last Posted Date
- 2021-02-02
- Target Recruit Count
- 15
- Registration Number
- NCT00586209
- Locations
- 🇺🇸
LA Biomed at Harbor-UCLA Medical Center, Torrance, California, United States
Effects on Glutamine on the Outcome of Allogeneic Bone Marrow Transplant Recipients
- Conditions
- First Posted Date
- 2007-11-26
- Last Posted Date
- 2010-07-07
- Lead Sponsor
- Hospital Authority, Hong Kong
- Target Recruit Count
- 40
- Registration Number
- NCT00563498
- Locations
- 🇨🇳
Queen Mary Hospital, Hong Kong, China
Efficacy of an Oral Formula in Prevention of Anti-cancer Therapy Side Effects
- Conditions
- First Posted Date
- 2007-04-03
- Last Posted Date
- 2013-06-05
- Lead Sponsor
- Société des Produits Nestlé (SPN)
- Registration Number
- NCT00455247
- Locations
- 🇫🇷
CRLCC Léon Bérard, Lyon, France
🇫🇷Institut Sainte-Catherine, Avignon, France
🇫🇷CRLC Val d'Aurelle, Montpellier, France
Glutamine in Treating Neuropathy Caused by Vincristine in Young Patients With Lymphoma, Leukemia, or Solid Tumors
- Conditions
- Interventions
- First Posted Date
- 2006-08-17
- Last Posted Date
- 2016-09-09
- Lead Sponsor
- Columbia University
- Target Recruit Count
- 56
- Registration Number
- NCT00365768
- Locations
- 🇺🇸
Herbert Irving Comprehensive Cancer Center at Columbia University Medical Center, New York, New York, United States
Glutamine in Preventing Oral Mucositis in Patients Receiving Chemotherapy for Sarcoma
- Conditions
- First Posted Date
- 2006-06-08
- Last Posted Date
- 2013-07-11
- Lead Sponsor
- Children's Oncology Group
- Registration Number
- NCT00334984
Enteral Glutamine in Critical Illness
- Conditions
- Interventions
- First Posted Date
- 2006-04-26
- Last Posted Date
- 2008-03-13
- Lead Sponsor
- Christiana Care Health Services
- Target Recruit Count
- 20
- Registration Number
- NCT00318331
- Locations
- 🇺🇸
Christiana Hospital, Newark, Delaware, United States
Drug Development Updates
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