Darbepoetin alfa
- Generic Name
- Darbepoetin alfa
- Brand Names
- Aranesp
- Drug Type
- Biotech
- CAS Number
- 209810-58-2
- Unique Ingredient Identifier
- 15UQ94PT4P
- Background
Human erythropoietin with 2 aa substitutions to enhance glycosylation (5 N-linked chains), 165 residues (MW=37 kD). Produced in Chinese hamster ovary (CHO) cells by recombinant DNA technology.
- Indication
For the treatment of anemia (from renal transplants or certain HIV treatment)
- Associated Conditions
- Anemia
Darbepoetin Treatment of Anemia in Children With Chronic Renal Failure
- First Posted Date
- 2005-09-21
- Last Posted Date
- 2013-08-26
- Lead Sponsor
- The Hospital for Sick Children
- Target Recruit Count
- 40
- Registration Number
- NCT00213291
- Locations
- 🇨🇦
The Hospital for Sick Children, Toronto, Ontario, Canada
Evaluation of Iron Supplementation During Darbepoetin Alfa Treatment in Prophylaxis of Severe Anaemia Chemo-Induced
- Conditions
- NeoplasmsAnemia
- First Posted Date
- 2005-09-21
- Last Posted Date
- 2006-11-14
- Lead Sponsor
- Institut Claudius Regaud
- Target Recruit Count
- 55
- Registration Number
- NCT00210002
- Locations
- 🇫🇷
Centre Hospitalier de Montauban, Montauban, France
🇫🇷Centre Hospitalier Joseph Ducuing, Toulouse, France
🇫🇷Institut Claudius Regaud, Toulouse, France
Darbepoetin Alfa in Patients With "Poor Prognosis" Germ Cell Tumor Treated With High-Dose Chemotherapy (HD-VIP)
- Conditions
- Dysgerminoma
- First Posted Date
- 2005-09-20
- Last Posted Date
- 2009-02-16
- Lead Sponsor
- University Hospital Tuebingen
- Target Recruit Count
- 108
- Registration Number
- NCT00204633
- Locations
- 🇩🇪
Medical Center II, University of Tuebingen, Tuebingen, Germany
Study for the Treatment of Anemia in Patients With Non-myeloid Malignancies Receiving Multicycle Chemotherapy.
- Conditions
- Anemia
- First Posted Date
- 2005-09-08
- Last Posted Date
- 2013-05-15
- Lead Sponsor
- Amgen
- Registration Number
- NCT00148421
Pegfilgrastim and Darbepoetin Alfa in Support of Adjuvant Chemotherapy for Breast Cancer
- Conditions
- Breast CancerStage I Breast CancerStage II Breast Cancer
- First Posted Date
- 2005-09-07
- Last Posted Date
- 2023-08-02
- Lead Sponsor
- Harold J. Burstein, MD, PhD
- Target Recruit Count
- 135
- Registration Number
- NCT00146562
- Locations
- 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States
🇺🇸Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States
🇺🇸Dana-Farber Cancer Institute, Boston, Massachusetts, United States
R-CHOP-14 Versus R-CHOP-21 and Darbepoetin Alpha in Patients Aged 60-80 Years With Diffuse Large B-cell Lymphoma
- First Posted Date
- 2005-09-05
- Last Posted Date
- 2015-09-02
- Lead Sponsor
- Lymphoma Study Association
- Target Recruit Count
- 600
- Registration Number
- NCT00144755
- Locations
- 🇨🇭
Schweirische Arbeitsgruppe fur klinische Krebsforschung, Lausanne, Switzerland
🇫🇷Hématologie CHU Purpan, Toulouse, France
🇫🇷Hématologie CHU de Lille, Lille, France
Flexibility: A Study to Assess the Impact of Darbepoetin Alfa in Subjects withNon-Myeloid Malignancies With Anemia Due to Chemotherapy
- Conditions
- AnemiaCancer
- First Posted Date
- 2005-09-05
- Last Posted Date
- 2013-05-24
- Lead Sponsor
- Amgen
- Target Recruit Count
- 750
- Registration Number
- NCT00144131
AIM 3: Anemia and Iron Management With Every 3 Week Dosing in Anemic Subjects With Nonmyeloid Malignancies
- Conditions
- Cancer
- First Posted Date
- 2005-08-26
- Last Posted Date
- 2013-05-23
- Lead Sponsor
- Amgen
- Registration Number
- NCT00135317
An Evaluation of Aranesp® in Subjects With Anaemic Chronic Kidney Disease (CKD)
- Conditions
- Kidney Disease
- First Posted Date
- 2005-07-27
- Last Posted Date
- 2008-06-16
- Lead Sponsor
- Amgen
- Registration Number
- NCT00124098
The Effect of Darbepoetin Upon Rehabilitation for Colorectal Cancer Surgery
- Conditions
- Colorectal Cancer
- First Posted Date
- 2005-07-22
- Last Posted Date
- 2006-07-07
- Lead Sponsor
- Herning Hospital
- Target Recruit Count
- 200
- Registration Number
- NCT00122720
- Locations
- 🇩🇰
Surgical Department, Odense University Hospital, Odense, Fyn, Denmark
🇩🇰Surgical Department, Aarhus University Hospital, Aarhus, Denmark
🇩🇰Surgical Department, Svendborg Hospital, Svendborg, Fyn, Denmark
Drug Development Updates
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