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Paquinimod

Generic Name
Paquinimod
Drug Type
Small Molecule
Chemical Formula
C21H22N2O3
CAS Number
248282-01-1
Unique Ingredient Identifier
HB76GLG27V
Background

Paquinimod is developed for the treatment of SLE (Systemic Lupus Erythematosus), which is an autoimmune disease. The disease affects mainly women of fertile age and progresses in flares with relatively symptom free periods in between. Current treatments of SLE are NSAID (nonsteroidal anti-inflammatory drugs), corticosteroids, antimalarians or cytotoxic drugs like for example Cyclophosphamide. The autoimmune attack affects several different organ systems and many patients suffer from serious secondary disease symptoms such as renal disorders as the disease progresses.

An Open-Label Study to Evaluate Biomarkers and Safety in Systemic Sclerosis Patients Treated With ABR-215757 (Paquinimod)

Phase 2
Completed
Conditions
Systemic Sclerosis
Interventions
First Posted Date
2011-12-07
Last Posted Date
2014-08-27
Lead Sponsor
Active Biotech AB
Target Recruit Count
9
Registration Number
NCT01487551

Exploratory Study of Changes in Disease Activity and Biomarkers With ABR-215757 in Patients With Mild Active Systemic Lupus Erythematosus (SLE)

Phase 2
Completed
Conditions
Systemic Lupus Erythematosus
Interventions
First Posted Date
2009-10-19
Last Posted Date
2015-06-25
Lead Sponsor
Active Biotech AB
Target Recruit Count
13
Registration Number
NCT00997100
Locations
🇸🇪

Lars Rönnblom M.D., Uppsala, Sweden

🇸🇪

Iva Gunnarsson M.D., Stockholm, Sweden

🇩🇰

Soren Jacobsen, Copenhagen, Denmark

and more 1 locations
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