哌泊溴烷

概览

An antineoplastic agent that acts by alkylation.

作用机制

The mechanism of action is uncertain, but due to the structural similarity with other DNA alkylating agents, pipobroman is thought to alkylate DNA leading to disruption of DNA synthesis and eventual cell death.

适应症

For the treatment of polycythaemia vera and refractory chronic myeloid leukaemia.

• Polycythemia