Gadobutrol
- Generic Name
- Gadobutrol
- Brand Names
- Gadavist, Gadovist
- Drug Type
- Small Molecule
- Chemical Formula
- C18H31GdN4O9
- CAS Number
- 770691-21-9
- Unique Ingredient Identifier
- 1BJ477IO2L
- Background
Intravenous gadobutrol is a second-generation extracellular non-ionic macrocyclic GBCA (gadolinium-based contrast agent) used in magnetic resonance imaging (MRI) in adults and children older than 2 years of age. It may help visualize and detect vascular abnormalities in the blood brain barrier (BBB) and central nervous system (CNS).
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- Indication
Gadobutrol is indicated for use with magnetic resonance imaging for the following diagnostic processes:
- Associated Conditions
- Arterial Occlusive Diseases of the Supra-aortic arteries, Coronary Artery Disease (CAD), Malignant Breast Neoplasm, Renal artery occlusion
- Associated Therapies
- -
A Study for Adults Undergoing Magnetic Resonance Imaging (MRI) for Known or Highly Suspected Brain and/or Spinal Cord Conditions
- Conditions
- Interventions
- First Posted Date
- 2024-12-12
- Last Posted Date
- 2024-12-12
- Lead Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
- Target Recruit Count
- 78
- Registration Number
- NCT06731829
- Locations
- 🇨🇳
People's Hospital, Peking University, Peking, Beijing, China
MR Image Synthesis With Low Gadobutrol Dose and AI
- First Posted Date
- 2024-01-25
- Last Posted Date
- 2024-07-03
- Lead Sponsor
- Subtle Medical
- Target Recruit Count
- 60
- Registration Number
- NCT06224543
- Locations
- 🇺🇸
Central Illinois Radiological Associates; OSF St. Francis Hospital Peoria, Peoria, Illinois, United States
🇺🇸UMass Chan Medical School, Worcester, Massachusetts, United States
🇺🇸The Pennsylvania State University, State College, Pennsylvania, United States
A Study to Compare How Well Gadoquatrane Works and Its Safety With an Already Available Contrast Agent for MRI in People With Any Known or Suspected Problems of the Body (Except Brain or Spinal Cord-related Problems)
- First Posted Date
- 2023-06-23
- Last Posted Date
- 2024-06-13
- Lead Sponsor
- Bayer
- Target Recruit Count
- 404
- Registration Number
- NCT05915728
- Locations
- 🇺🇸
Boston Medical Center, Boston, Massachusetts, United States
🇺🇸Houston Methodist Hospital, Houston, Texas, United States
🇨🇳The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, China
A Study to Compare How Well Gadoquatrane Works and Its Safety With an Already Available Contrast Agent for MRI in People With Known or Suspected Brain or Spinal Cord-related Problems
- First Posted Date
- 2023-06-23
- Last Posted Date
- 2024-06-13
- Lead Sponsor
- Bayer
- Target Recruit Count
- 303
- Registration Number
- NCT05915702
- Locations
- 🇺🇸
Halo Diagnostics, Indian Wells, California, United States
🇺🇸Biogenix Molecular, LLC, Miami, Florida, United States
🇺🇸Duke University School of Medicine, Durham, North Carolina, United States
Phenotyping Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) by Intravesical Contrast Enhanced - Magnetic Resonance Imaging (ICE-MRI) Bladder Permeability Assay
- Conditions
- Interventions
- First Posted Date
- 2023-04-13
- Last Posted Date
- 2023-09-21
- Lead Sponsor
- Christopher J Chermansky, MD
- Target Recruit Count
- 30
- Registration Number
- NCT05811377
- Locations
- 🇺🇸
UPMC Magee Women's Hospital, Pittsburgh, Pennsylvania, United States
PSMA-Targeted 18F-DCFPyL PET/MRI for the Detection of Prostate Cancer
- Conditions
- Interventions
- First Posted Date
- 2021-06-02
- Last Posted Date
- 2022-08-03
- Lead Sponsor
- Northwestern University
- Target Recruit Count
- 106
- Registration Number
- NCT04910425
- Locations
- 🇺🇸
Northwestern University, Chicago, Illinois, United States
Novel Imaging Technique to Assess Gynecologic Cancer
- First Posted Date
- 2021-05-19
- Last Posted Date
- 2024-01-05
- Lead Sponsor
- Memorial Sloan Kettering Cancer Center
- Target Recruit Count
- 70
- Registration Number
- NCT04893434
- Locations
- 🇺🇸
Memorial Sloan Kettering Bergen (All Protocol Activities), Montvale, New Jersey, United States
🇺🇸Memorial Sloan Kettering Nassau (All Protocol Activities), Uniondale, New York, United States
🇺🇸Memorial Sloan Kettering Cancer Center, New York, New York, United States
Effect on Body Movement and Mental Skills in Patients Who Received Gadolinium-based Contrast Media for Magnetic Resonance Examination Multiple Times Within 5 Years
- Conditions
- Interventions
- First Posted Date
- 2020-05-04
- Last Posted Date
- 2024-05-17
- Lead Sponsor
- Guerbet
- Target Recruit Count
- 2076
- Registration Number
- NCT04373564
- Locations
- 🇺🇸
Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States
🇺🇸UT Southwestern Medical Center, Dallas, Texas, United States
🇧🇷Hospital Santa Marta, Taguatinga, Distrito Federal, Brazil
PET/MRI Scan for the Evaluation of Resectable Stage IA1-IB3 Cervical Cancer
- Conditions
- Interventions
- First Posted Date
- 2020-01-07
- Last Posted Date
- 2024-11-27
- Lead Sponsor
- M.D. Anderson Cancer Center
- Target Recruit Count
- 25
- Registration Number
- NCT04219904
- Locations
- 🇺🇸
M D Anderson Cancer Center, Houston, Texas, United States
Novel MRI Techniques for the Characterization and Treatment Assessment of High Grade Brain Lesions
- Conditions
- Interventions
- First Posted Date
- 2019-10-21
- Last Posted Date
- 2022-11-21
- Lead Sponsor
- M.D. Anderson Cancer Center
- Target Recruit Count
- 6
- Registration Number
- NCT04132843
- Locations
- 🇺🇸
M D Anderson Cancer Center, Houston, Texas, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.