Micafungin
- Generic Name
- Micafungin
- Brand Names
- Mycamine
- Drug Type
- Small Molecule
- Chemical Formula
- C56H71N9O23S
- CAS Number
- 235114-32-6
- Unique Ingredient Identifier
- R10H71BSWG
- Background
Micafungin is an antifungal drug. It belongs to the antifungal class of compounds known as echinocandins and exerts its effect by inhibiting the synthesis of 1,3-beta-D-glucan, an integral component of the fungal cell wall.
- Indication
Indicated for the treatment of candidemia, acute disseminated candidiasis, and certain other invasive Candida infections, as well as esophageal candidiasis, and prophylaxis of Candida infections in patients undergoing hematopoietic stem cell transplantation. Micafungin is also used as an alternative for the treatment of oropharyngeal candidiases and has been...
- Associated Conditions
- Abscesses, Aspergillosis, Candidemia, Candidiasis, Esophageal Candidiasis, Fungal Infections, Fungal peritonitis caused by Candida, Acute disseminated Candidiasis
- Associated Therapies
- -
Antifungal Prophylaxis With Micafungin After Cord Blood Allogeneic Stem Cell Transplantation (MycaCOORD)
- First Posted Date
- 2013-06-27
- Last Posted Date
- 2016-05-20
- Lead Sponsor
- Nantes University Hospital
- Target Recruit Count
- 21
- Registration Number
- NCT01888458
- Locations
- 🇫🇷
CHU de Nantes, Nantes, France
Pharmacokinetics of Micafungin in Patients Intensive Care Unit
- First Posted Date
- 2013-02-04
- Last Posted Date
- 2020-11-30
- Lead Sponsor
- Radboud University Medical Center
- Target Recruit Count
- 20
- Registration Number
- NCT01783379
- Locations
- 🇳🇱
Rijstate Hospital, Arnhem, Netherlands
🇳🇱Gelderse Vallei Hospital, Ede, Netherlands
🇳🇱Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands
Empirical Antifungal Treatment in ICUS
- First Posted Date
- 2013-01-23
- Last Posted Date
- 2015-03-24
- Lead Sponsor
- University Hospital, Grenoble
- Target Recruit Count
- 260
- Registration Number
- NCT01773876
- Locations
- 🇫🇷
University Hospital of Avicennes, Bobigny, France
🇫🇷Hospital University of Besançon, Besançon, France
🇫🇷Hospital University of Clermont Ferrand, Clermont Ferrand, France
Pharmacokinetics of Micafungin in Children on Extracorporeal Membrane Oxygenation
- First Posted Date
- 2012-08-16
- Last Posted Date
- 2019-11-05
- Lead Sponsor
- Kevin Watt
- Target Recruit Count
- 18
- Registration Number
- NCT01666769
- Locations
- 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States
Micafungin Prevention Study for Invasive Fungal Disease in Pediatric & Adolescent Patients Undergoing Autologous Hematopoietic Stem Cell Transplantation
- First Posted Date
- 2011-08-16
- Last Posted Date
- 2014-07-14
- Lead Sponsor
- Seoul National University Hospital
- Target Recruit Count
- 112
- Registration Number
- NCT01417169
- Locations
- 🇰🇷
Seoul National University Hospital, Seoul, Chongno-gu, Korea, Republic of
Posaconazole Versus Micafungin for Prophylaxis Against Invasive Fungal Infections During Neutropenia in Patients Undergoing Chemotherapy for Acute Myelogenous Leukemia, Acute Lymphocytic Leukemia or Myelodysplastic Syndrome
- Conditions
- Interventions
- First Posted Date
- 2010-09-13
- Last Posted Date
- 2018-05-07
- Lead Sponsor
- Memorial Sloan Kettering Cancer Center
- Target Recruit Count
- 113
- Registration Number
- NCT01200355
- Locations
- 🇺🇸
Memorial Sloan Kettering Cancer Center, New York, New York, United States
Micafungin Prevention Study for Fungal Disease in Child Receiving Allogenic Hematopoietic Stem Cell Transplantation
- Conditions
- Interventions
- First Posted Date
- 2010-06-03
- Last Posted Date
- 2010-09-28
- Lead Sponsor
- Asan Medical Center
- Target Recruit Count
- 145
- Registration Number
- NCT01135589
A Study to Evaluate Pre-emptive Treatment for Invasive Candidiasis in High Risk Surgical Subjects
- First Posted Date
- 2010-05-13
- Last Posted Date
- 2024-11-19
- Lead Sponsor
- Astellas Pharma Inc
- Target Recruit Count
- 252
- Registration Number
- NCT01122368
Drug Concentration Analysis of Micafungin in Overweight, Obese, and Extremely Obese Volunteers
- First Posted Date
- 2010-03-19
- Last Posted Date
- 2020-11-27
- Lead Sponsor
- University of Texas Southwestern Medical Center
- Target Recruit Count
- 36
- Registration Number
- NCT01090141
- Locations
- 🇺🇸
University of Texas Southwestern Medical Center, Dallas, Texas, United States
Liver Transplant European Study Into the Prevention of Fungal Infection
- Conditions
- Interventions
- First Posted Date
- 2010-01-28
- Last Posted Date
- 2024-11-18
- Lead Sponsor
- Astellas Pharma Inc
- Target Recruit Count
- 350
- Registration Number
- NCT01058174
Drug Development Updates
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