Abciximab

Generic Name
Abciximab
Brand Names
-
Drug Type
Biotech
Chemical Formula
-
CAS Number
143653-53-6
Unique Ingredient Identifier
X85G7936GV
Background

Abciximab is a Fab fragment of the chimeric human-murine monoclonal antibody 7E3. Abciximab binds to the glycoprotein (GP) IIb/IIIa receptor of human platelets and inhibits platelet aggregation by preventing the binding of fibrinogen, von Willebrand factor, and other adhesive molecules. It also binds to vitronectin (αvβ3) receptor found on platelets and vess...

Indication

Abciximab is indicated as an adjunct to percutaneous coronary intervention for the prevention of cardiac ischemic complications in patients undergoing percutaneous coronary intervention and in patients with unstable angina not responding to conventional medical therapy when percutaneous coronary intervention is planned within 24 hours. Abciximab is intended ...

Associated Conditions
Ischemic cardiovascular events
Associated Therapies
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