Lisdexamfetamine
- Generic Name
- Lisdexamfetamine
- Brand Names
- Vyvanse
- Drug Type
- Small Molecule
- Chemical Formula
- C15H25N3O
- CAS Number
- 608137-32-2
- Unique Ingredient Identifier
- H645GUL8KJ
- Background
Lisdexamfetamine is a prodrug of dextroamphetamine, a central nervous system stimulant known as d-amphetamine, covalently attached to the naturally occurring amino acid L-lysine. Lisdexamfetamine is the first chemically formulated prodrug stimulant and was first approved by the FDA in April 2008. It was also approved by Health Canada in February 2009. Lisde...
- Indication
Lisdexamfetamine is indicated for the treatment of attention deficit hyperactivity disorder (ADHD) in adults and pediatric patients six years and older. It is also indicated to treat moderate to severe binge eating disorder (BED) in adults. It is approved for use in the US and Canada.
- Associated Conditions
- Attention Deficit Hyperactivity Disorder (ADHD), Moderate Binge Eating Disorder (BED), Severe Binge Eating Disorder (BED)
- Associated Therapies
- -
Characterization and Sequential Pharmacotherapy of Severe Mood Dysregulation
- Conditions
- Interventions
- First Posted Date
- 2012-10-25
- Last Posted Date
- 2018-02-26
- Lead Sponsor
- University of California, Los Angeles
- Target Recruit Count
- 34
- Registration Number
- NCT01714310
- Locations
- 🇺🇸
UCLA Semel Institute, Los Angeles, California, United States
Open Label Extension in Adults With Binge Eating Disorder (BED)
- First Posted Date
- 2012-08-03
- Last Posted Date
- 2021-06-09
- Lead Sponsor
- Shire
- Target Recruit Count
- 604
- Registration Number
- NCT01657019
- Locations
- 🇺🇸
Southwestern Research, Inc., Beverly Hills, California, United States
🇺🇸Birmingham Research Group, Birmingham, Alabama, United States
🇺🇸TRIMED Clinical Trials, Corona, California, United States
Effectiveness of Vyvanse Compared to Concerta in Adolescents With Attention-deficit/Hyperactivity Disorder
- Conditions
- Interventions
- First Posted Date
- 2012-03-13
- Last Posted Date
- 2021-06-08
- Lead Sponsor
- Shire
- Target Recruit Count
- 464
- Registration Number
- NCT01552915
- Locations
- 🇺🇸
Amedica Research Institute, Hialeah, Florida, United States
🇺🇸Pacific Clinical Research Medical Group, Orange, California, United States
🇺🇸Fidelity Clinical Research, Inc., Lauderhill, Florida, United States
Effectiveness of Vyvanse Compared to Concerta in Adolescents With Attention-deficit/Hyperactivity Disorder
- Conditions
- Interventions
- First Posted Date
- 2012-03-13
- Last Posted Date
- 2021-06-10
- Lead Sponsor
- Shire
- Target Recruit Count
- 549
- Registration Number
- NCT01552902
- Locations
- 🇺🇸
Center for Advanced Improvement, Tucson, Arizona, United States
🇺🇸Clinical Study Centers, LLC, Little Rock, Arkansas, United States
🇺🇸Coastal Connecticut Research, LLC, New London, Connecticut, United States
Pilot Study of Lisdexamfetamine for Treatment of Cocaine Dependence
- First Posted Date
- 2011-12-12
- Last Posted Date
- 2019-07-15
- Lead Sponsor
- University of Minnesota
- Target Recruit Count
- 43
- Registration Number
- NCT01490216
- Locations
- 🇺🇸
University of Minnesota, Minneapolis, Minnesota, United States
Open-Label Pilot Study of Lisdexamfetamine for Cocaine Dependence
- Conditions
- Interventions
- First Posted Date
- 2011-12-07
- Last Posted Date
- 2019-04-24
- Lead Sponsor
- New York State Psychiatric Institute
- Target Recruit Count
- 17
- Registration Number
- NCT01486810
- Locations
- 🇺🇸
STARS, New York, New York, United States
Imaging the Effects of Stimulant Medication on Emotional Lability in Patients With ADHD
- Conditions
- Interventions
- First Posted Date
- 2011-08-12
- Last Posted Date
- 2022-08-02
- Lead Sponsor
- New York State Psychiatric Institute
- Target Recruit Count
- 117
- Registration Number
- NCT01415440
- Locations
- 🇺🇸
New York State Psychiatric Institute, New York, New York, United States
Effects of LDX on Functioning of College Students With ADHD
- Conditions
- Interventions
- First Posted Date
- 2011-04-27
- Last Posted Date
- 2014-04-08
- Lead Sponsor
- University of Rhode Island
- Target Recruit Count
- 50
- Registration Number
- NCT01342445
- Locations
- 🇺🇸
Department of Psychology, University of Rhode Island, Kingston, Rhode Island, United States
🇺🇸Department of Education and Human Services, Lehigh University, Bethlehem, Pennsylvania, United States
Lisdexamfetamine Dimesylate 2-year Safety Study in Children and Adolescents With Attention-Deficit/Hyperactivity Disorder (ADHD)
- Conditions
- Interventions
- First Posted Date
- 2011-04-05
- Last Posted Date
- 2021-06-10
- Lead Sponsor
- Shire
- Target Recruit Count
- 314
- Registration Number
- NCT01328756
- Locations
- 🇩🇪
Albert-Ludwigs-Universität Freiburg, Freiburg, Baden-Wuerttemberg, Germany
🇩🇪Schwerpunktpraxis für Entwicklung und Lernen, Bamberg, Bayern, Germany
🇩🇪Universitätsmedizin Berlin, Berlin, Germany
Attention & Memory Impairments in Menopausal Women
- Conditions
- Interventions
- First Posted Date
- 2011-03-28
- Last Posted Date
- 2017-06-28
- Lead Sponsor
- University of Pennsylvania
- Target Recruit Count
- 35
- Registration Number
- NCT01324024
- Locations
- 🇺🇸
Penn Center for Women's Behavioral Wellness, Philadelphia, Pennsylvania, United States
Drug Development Updates
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