Midomafetamine

Generic Name
Midomafetamine
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C11H15NO2
CAS Number
42542-10-9
Unique Ingredient Identifier
KE1SEN21RM
Background

An N-substituted amphetamine analog. It is a widely abused drug classified as a hallucinogen and causes marked, long-lasting changes in brain serotonergic systems. It is commonly referred to as MDMA or ecstasy. It is a widely abused drug classified as a hallucinogen and causes marked, long-lasting changes in brain serotonergic systems.

Indication

Clinical trials are now testing the therapeutic potential of MDMA for post-traumatic stress disorder (PTSD) and anxiety associated with terminal cancer. MDMA is one of the four most widely used illicit drugs in the U.S.

Associated Conditions
-
Associated Therapies
-
Clinical Trials
Related News

MDMA in Borderline Personality Disorder

Phase 2
Not yet recruiting
Conditions
Borderline Personality Disorder
Interventions
Drug: MDMA
First Posted Date
2024-11-11
Last Posted Date
2024-11-12
Lead Sponsor
Yale University
Target Recruit Count
10
Registration Number
NCT06683014
Locations
🇺🇸

Connecticut Mental Health Center, New Haven, Connecticut, United States

Dose Optimization of MDMA-Assisted Therapy for PTSD

First Posted Date
2024-05-17
Last Posted Date
2024-05-17
Lead Sponsor
Bronx VA Medical Center
Target Recruit Count
60
Registration Number
NCT06418178

MDMA-Assisted Psychotherapy for Treatment Resistant PTSD in Adolescents

First Posted Date
2024-04-09
Last Posted Date
2024-04-09
Lead Sponsor
University of California, Los Angeles
Target Recruit Count
10
Registration Number
NCT06353282
Locations
🇺🇸

UCLA Semel Institute for Neuroscience and Human Behavior, Los Angeles, California, United States

Epigenetics and MDMA-Assisted Psychotherapy for PTSD

Phase 3
Active, not recruiting
Conditions
PTSD
Interventions
Drug: MDMA
Behavioral: Psychotherapy
First Posted Date
2024-01-03
Last Posted Date
2024-01-03
Lead Sponsor
University of Southern California
Target Recruit Count
45
Registration Number
NCT06189027
Locations
🇺🇸

Univeristy of Southern California, Los Angeles, California, United States

MDMA-assisted Therapy for Fibromyalgia

Early Phase 1
Not yet recruiting
Conditions
Fibromyalgia
First Posted Date
2023-10-04
Last Posted Date
2024-04-12
Lead Sponsor
Spaulding Rehabilitation Hospital
Target Recruit Count
20
Registration Number
NCT06066853
Locations
🇺🇸

Massachusetts General Hospital, Charlestown, Massachusetts, United States

Group MDMA-therapy for Veterans With PTSD

Phase 1
Active, not recruiting
Conditions
PTSD
Interventions
Drug: MDMA
Behavioral: Group Therapy
First Posted Date
2023-07-27
Last Posted Date
2024-08-21
Lead Sponsor
Portland VA Research Foundation, Inc
Target Recruit Count
23
Registration Number
NCT05961527
Locations
🇺🇸

Portland-Vancouver VA, Vancouver, Washington, United States

Prosocial Effects of MDMA

Early Phase 1
Completed
Conditions
MDMA ('Ecstasy')
Social Interaction
Interventions
Drug: Placebo
Drug: MDMA
First Posted Date
2023-07-17
Last Posted Date
2024-08-19
Lead Sponsor
University of Chicago
Target Recruit Count
33
Registration Number
NCT05948683
Locations
🇺🇸

University of Chicago, Chicago, Illinois, United States

MDMA for AUD/PTSD Comorbidity

Phase 2
Recruiting
Conditions
Alcohol Use Disorder
Post Traumatic Stress Disorder
Interventions
Drug: MDMA
First Posted Date
2023-07-13
Last Posted Date
2024-08-20
Lead Sponsor
Carolina L Haass-Koffler
Target Recruit Count
18
Registration Number
NCT05943665
Locations
🇺🇸

Brown University, Providence, Rhode Island, United States

MDMA-assisted Therapy Versus Cognitive Processing Therapy for Veterans with Severe Posttraumatic Stress Disorder

First Posted Date
2023-05-01
Last Posted Date
2024-11-11
Lead Sponsor
Patricia Suppes
Target Recruit Count
30
Registration Number
NCT05837845
Locations
🇺🇸

VA Palo Alto Health Care System / Stanford University, Palo Alto, California, United States

MDMA-Assisted Therapy for Veterans With Moderate to Severe Post Traumatic Stress Disorder

First Posted Date
2023-03-30
Last Posted Date
2023-03-30
Lead Sponsor
Stephen Robert Marder
Target Recruit Count
40
Registration Number
NCT05790239
Locations
🇺🇸

VA Greater Los Angeles Healthcare System, Westwood campus, Los Angeles, California, United States

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